Elevated Uric Acid Increases the Risk for Acute Kidney Injury

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Presentation transcript:

Elevated Uric Acid Increases the Risk for Acute Kidney Injury Vijay Lapsia, MD, Richard J. Johnson, MD, Bhagwan Dass, MD, Michiko Shimada, MD, PhD, Ganesh Kambhampati, MD, Noel I. Ejaz, Amir A. Arif, A. Ahsan Ejaz, MD The American Journal of Medicine Volume 125, Issue 3, Pages 302.e9-302.e17 (March 2012) DOI: 10.1016/j.amjmed.2011.06.021 Copyright © 2012 Elsevier Inc. Terms and Conditions

Figure 1 Incidence of acute kidney injury (AKI) as a function of preoperative serum uric acid (SUA). The American Journal of Medicine 2012 125, 302.e9-302.e17DOI: (10.1016/j.amjmed.2011.06.021) Copyright © 2012 Elsevier Inc. Terms and Conditions

Figure 2 Risk for acute kidney injury by threshold serum uric acid levels. CI=95% confidence interval. The American Journal of Medicine 2012 125, 302.e9-302.e17DOI: (10.1016/j.amjmed.2011.06.021) Copyright © 2012 Elsevier Inc. Terms and Conditions

Figure 3 Influence of serum uric acid on odds ratios (OR) for acute kidney injury in subgroups. CABG=coronary artery bypass graft; GFR = glomerular filtration rate; LVEF = left ventricular ejection fraction; TAA = thoracic aortic aneurysm. The American Journal of Medicine 2012 125, 302.e9-302.e17DOI: (10.1016/j.amjmed.2011.06.021) Copyright © 2012 Elsevier Inc. Terms and Conditions

Figure 4 Forty-eight-hour peak serum creatinine (SCr) and hospital peak SCr. The American Journal of Medicine 2012 125, 302.e9-302.e17DOI: (10.1016/j.amjmed.2011.06.021) Copyright © 2012 Elsevier Inc. Terms and Conditions

Figure 5 Serum uric acid (SUA) and length of stay and days on ventilation. The American Journal of Medicine 2012 125, 302.e9-302.e17DOI: (10.1016/j.amjmed.2011.06.021) Copyright © 2012 Elsevier Inc. Terms and Conditions