ROCK (Research on Osteochondritis Dissecans of the Knee) 5th Annual Research Meeting Denver, 2015 Kevin Shea, M.D. St. Luke’s Health System Boise, ID.

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Presentation transcript:

ROCK (Research on Osteochondritis Dissecans of the Knee) 5th Annual Research Meeting Denver, 2015 Kevin Shea, M.D. St. Luke’s Health System Boise, ID

Study Group – Osteochondritis Dissecans Limited high quality clinical research published last 30 years Vast majority of research is retrospective case review, and expert opinion

Osteochondritis Dissecans Research Group - History OCD Research Group, aka ROCK Discussion 2009 Ted Ganley Eric Wall OCD Clinical Practice Guideline 2009-2010 – Core Group – Kurt Spindler recommended Jim Carey First Meeting, Chicago, November 2010 – AAOS OREF Education Grant – Kristy Weber ROCK Name – AOSSM 2011 Wright, Carey

Osteochondritis Dissecans 2010 AAOS Clinical Practice Guideline for OCD of the Knee Identified the important clinical questions, and areas in need of more research Provides outline for future research Perfect Opportunity for Research Group

Goals - ROCK Group Improve the quality of life in patients with this condition Develop Optimal prevention and treatment strategies for OCD Reduce Variation in Care ----- Meeting Notes (1/25/13 13:58) ----- sadffasdf

OCD Future Research Recommendations from CPG Inter- and intra-observer reliability studies for radiographs, MRI, and arthroscopy classification Prospective cohort studies to identify the independent predictors of healing RCTs to establish the optimal surgical and nonsurgical treatment strategies

ROCK Vail/Denver Meeting 2011

ROCK AOSSM 2011 Select Database Commitment for Funding Refine Research Questions

Osteochondritis Dissecans- Definition 2011 A focal, idiopathic alteration of sub-chondral bone with risk for instability and disruption of adjacent articular cartilage that may result in premature osteoarthritis Published CORR 2013 Edmonds Editorial

Osteochondritis Dissecans Research Group - Milestones RCT – 2012 Ben Heyworth 2014 - Met AOSSM enrollment criteria – Barely! ROCK Mission Statement 2013 The Research on Osteochondritis Dissecans of the Knee (ROCK) Study Group is devoted to the investigation of etiology, diagnostic criteria, management, and optimization of physical activity for patients with OCD. Prospective Cohort 2014 Instructional Course Lectures AAOS, AOSSM, POSNA 2011-2015

ROCK Centers 2009 - 2015 2009 - 3 ‘Centers’ 2013 - 16 Centers, US, Canada, Singapore, Sweden, Germany 20 ORS, 3 MSK Radiologists, 2 PTs, 2 med students, PhD/ATC

ROCK Progress: Reliability Studies Arthroscopy Classification Self-Funded Study Complete 2013 ICC Reliability Scores 0.91-.95 Presented AOSSM POSNA 2013. Publication Submission Pending Healing Sequence AOSSM Grant Status. Ongoing. Completion 2015 X-ray Classification Completion Mid 2013. Published 1-2015 MRI Classification AOSSM Grant Completion 2016

ROCK Member Publications CORR Symposium on OCD Edmonds Group Publications on OCD (Jan 2015) 79 total publications (up from 54 at Denver 2014) 39 collaborative publications (more than 1 ROCK member; up from 20 at Denver 2014)

ROCK Research Fellowship 2014 Jake Jacobs Funding – Anderson, Ganley, Shea Utah Population Database OCD study – cross reference of diagnoses and family geneology records: Jacobs, Ganley, Anderson, Shea Ongoing. OCD epidemiology studies at Kaiser-Permanente Southern California: Weiss, Kessler, Jacobs, Shea. OCD Knee OCD Other OCD Progression to Surgery OCD Adult OCD – Growth Hormone -Multiple studies on pediatric knee ligament and physeal anatomy: Ganley, Shea, Anderson, Styhl, Jacobs

ROCK Research Fellowship 2015 2 superb applicants – first year medical students Boise Summer 2015 Other Centers?

ROCK Future Add Additional Centers Treatment Variation Reduction Prospective Cohort Studies and Expansion Funding OREF Industry AUC for OCD Other