Multiple factors contributing to the epigenetics of the “new” bronchopulmonary dysplasia (BPD) associated with lung development and gestational and postnatal.

Slides:

Advertisements

Similar presentations

Neonatal Mechanical Ventilation

Advertisements

Bronchopulmonary Dysplasia(BPD) Kumari Weeratunge M.D. PL - 2.

Mechanical Ventilation in the Neonate RC 290 CPAP Indications: Refractory Hypoxemia –PaO2 –Many hospitals use 50% as the upper limit before changing.

Ventilator Settings in Pediatric Patients Wanida Paoin Thammasat Hospital,Thammasat University.

Measuring Neonatal Lung Volume

Respiratory support and respiratory outcome in preterm infants PD Dr. med. Ulrich Thome Division of Neonatolgy and Pediatric Critical Care University Children’s.

Principles of Mechanical Ventilation Magdy M Khalil, MD, EDIC Prof. Pulmonary& Critical Care Medicine.

A,B: Two systems for transtracheal jet ventilation after cricothyrotomy (see Figure 55-5). A jet ventilator and pressure regulator (as shown in A) provide.

REPRODUCED WITH PERMISSION FROM BRITISH JOURNAL OF SPORTS MEDICINE162

ASIA (American Spinal Injury Association) classification

25 – 26 March 2013 University of Oxford Intubation or CPAP ?

Feeding in Very Low Birth Weight neonates on Vapotherm versus CPAP

Esophageal pressure measurements in a patient with auto–positive end-expiratory pressure (auto-PEEP). Note that an esophageal pressure decrease of approximately.

Reproduced with permission from British Journal of Sports Medicine

The Ontario Lung Association Pediatric Asthma Care Pathway

Selector switch of the Datex-Ohmeda Aestiva 5 machine

The two-point calibration procedure

Comparison of lungs excised from rats ventilated with peak pressure of 14 cm H2O, zero positive end-expiratory pressure (PEEP); peak pressure 45 cm H2O,

Transection of the utero-ovarian ligament

Risk designation of full-term and near-term newborns based on their hour-specific bilirubin values. (Reproduced, with permission, from Bhutani VK et al:

(Reproduced with permission from Jemal A, et al: Cancer statistics, CA Cancer J Clin 58:71, 2008.) Source: Chapter 17. The Breast, Schwartz's Principles.

Virtual integration involves contractual links between HMOs and physician groups, hospitals, and other provider units. Source: How Health Care Is Organized—II:

(Reproduced, with permission, from Findling JW, et al

Pathogenesis of bone diseases in chronic kidney disease

(Reproduced, with permission, from Findling JW

Alla Kushnir, MD, Judy Saslow MD, Linda Slater-Myer, MD

Third law of high-frequency ventilation

Left. CT scan slices obtained after oleic acid injury of the lung superimposed on the pressure-volume relationship of the respiratory system. Consolidation.

Algorithm for the management of aortic valve stenosis

(Reproduced with permission from Lau TL, Kim C, Ginsberg MH, et al

In diastolic dysfunction, the diastolic pressure-volume relationship is shifted upward and to the left (dashed line), which leads to an elevated left ventricular.

Effect of gas density on aerosol delivery from a pressurized metered-dose inhaler (pMDI) and jet nebulizer. A. Albuterol was administered via a pMDI and.

REPRODUCED WITH PERMISSION OF BRITISH JOURNAL OF SPORTS MEDICINE

Comparative serum steroid (CSS) levels of norelgestromin (NGMN) and ethinyl estradiol (EE) following patch administration. (Reproduced with permission.

The stages of Reproductive Aging Workshop +10 staging system for reproductive aging in women. (Reproduced with permission from Harlow SD, Gass M, Hall.

(Reproduced from Maisels MJ. Why use homeopathic doses of phototherapy

Pneumatic schematic of the Dräger Infinity V500 intensive care ventilator. A. Gas-mixture and gas-metering assembly. Gas from the supply lines enters the.

Effect of pressure support (PS) and continuous positive airway pressure (CPAP) on frequency-to-tidal volume ratio (f/VT). Left panel: In twelve patients.

Criteria used to determine breath types during mechanical ventilation

Epidermolysis bullosa (EB)

Kaplan-Meier survival for adult heart transplants performed between January 1982 and June 2006 by era. All comparisons are significant at p < (Reproduced.

Infants With Bronchopulmonary Dysplasia Have Fewer Pro-Angiogenic Circulating Progenitor Cells And Decreased Pulmonary Diffusion RS Tepper, C Tiller, J.

(Adapted and reprinted with permission, from Hughes JM et al: Effect of lung volume on the distribution of pulmonary blood flow in man. Respir Physiol.

Adapted with permission from Hsia, J et al

A Pavlik harness is used to treat infants with developmental dysplasia of the hip. Source: Orthoses for Paraplegia or Hip Impairments, Prosthetics & Orthotics.

Recommendations for instituting high-frequency oscillatory ventilation (HFOV) and the transition to conventional ventilation during weaning. CXR, chest.

Outcomes in Neonates with Hypoxemic Refractory Respiratory Failure on High-Frequency Oscillatory Ventilator versus High-Frequency Jet Ventilator Alla Kushnir.

Relationship of oxygenation, as reflected in the ratio of the arterial and alveolar oxygen tensions (a/A ratio), to the mean airway pressure (mPaw) applied.

The Effects of PEEP on Oxygenation during One-Lung Ventilation

[From: Galli : et al: Emergency Orthopedics: The Spine

Number of uninsured persons in the United States, 1980 to 2014 (U. S

Measurement of static and dynamic compliance during mechanical ventilation. A tidal volume is delivered, causing a peak in airway pressure; dynamic compliance.

(Reproduced, with permission, from Fulop M, et al

A, Pyrimethamine serum levels (4 and 24 hours after a dose) of children given 1 mg pyrimethamine per kilogram daily. B, Pyrimethamine serum levels (4 and.

The Pediatrix BabySteps® Data Warehouse and the Pediatrix QualitySteps Improvement Project System—Tools for “Meaningful Use” in Continuous Quality Improvement

Chart 1: Oxygen prescription for acutely hypoxaemic patients in hospital. Chart 1: Oxygen prescription for acutely hypoxaemic patients in hospital. ABG,

Francisco Igor B. Macedo, MD, Enisa M

Robert H. Pfister, MD, Jay P. Goldsmith, MD Clinics in Perinatology

Measured values of a) inspiratory volume, b) PEEP, c) FIO2 and d) respiratory rate delivered to a test lung by several devices in four intensive care units.

Lung simulator diagram of airway pressure release ventilation (APRV): volume (yellow), lung pressure (white), and flow (orange)/time curve. Lung simulator.

Why the Bronchopulmonary Dysplasia Improvement Curve Lags Behind

Pressure-controlled ventilation improves oxygenation during laparoscopic obesity surgery compared with volume-controlled ventilation P. Cadi, T. Guenoun,

Kaplan-Meier curves. Kaplan-Meier curves. Assuming the fraction of inspired oxygen (Fio 2) = 0.21 as the event, the probability of remaining supplementary.

A) Tidal volume (VT) (presented as % predicted of vital capacity (VC)), b) breathing frequency (Fb), c) dynamic inspiratory capacity (IC) and d) inspiratory.

A 2-min recording showing periodic breathing, stable delivered pressure, and fluctuating oxygen saturation in a premature neonate supported by nasal intermittent.

Lung function adjusted for body length and gestational age in male and female premature infants. Lung function adjusted for body length and gestational.

The Pediatrix BabySteps® Data Warehouse and the Pediatrix QualitySteps Improvement Project System—Tools for “Meaningful Use” in Continuous Quality Improvement

Study flow chart and pathway.

Depiction of an expiratory flow curve.

Initial protocol for daily dangle

Presentation transcript:

Multiple factors contributing to the epigenetics of the “new” bronchopulmonary dysplasia (BPD) associated with lung development and gestational and postnatal developmental periods. FIO2, fraction of inspired oxygen; VT, tidal volume; CPAP, continuous positive airway pressure; PEEP, positive end-expiratory pressure; NICU, neonatal intensive care unit; IMV, invasive mechanical ventilation; HIFI, High Frequency Ventilation in Premature Infants study; VEGF, vascular endothelial growth factor; FEV1, forced expiratory volume in 1 second. (Reproduced with permission from Merritt et al.3) Source: Lungs, Neonatology: Clinical Practice and Procedures Citation: Stevenson DK, Cohen RS, Sunshine P. Neonatology: Clinical Practice and Procedures; 2015 Available at: http://accesspediatrics.mhmedical.com/DownloadImage.aspx?image=/data/books/1462/ste_ch86_f002.png&sec=85596375&BookID=1462&ChapterSecID=82246423&imagename= Accessed: October 08, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved