Circumscribed palmar or plantar hypokeratosis: A distinctive epidermal malformation of the palms or soles Amparo Pérez, MDa, Arno Rütten, MDb, Reinhard.

Slides:

Advertisements

Similar presentations

Topically applied ascorbic acid solution for the treatment of basal cell carcinoma (BCC) Péter Holló, MD, PhD, Hajnalka Jókai, MD, PhD, Judit Hársing,

Advertisements

Grover disease with a contagious twist

Steven Q. Wang, MD, Leonard H. Goldberg, MD, FRCP

Easwar Natarajan, BDS, DMSc, Sook-Bin Woo, DMD

Dermatopathology and molecular genetics

Low-dose methotrexate-induced ulcerated psoriatic plaques: A rare case

Simultaneous development and parallel course of disseminated superficial porokeratosis and ovarian cancer: Coincidental association or true paraneoplastic.

CD47 expression for in situ and invasive cutaneous epithelial lesions

A 52-year-old man with bullous pemphigoid and bullous cystitis

Systematized linear porokeratosis: A rare variant of diffuse porokeratosis with good response to systemic acitretin Jin-Bon Hong, MD, Cheng-Hsiang Hsiao,

Infliximab-induced eczematid-like purpura of Doucas and Kapetenakis∗∗Previously presented at the Chicago Dermatological Society meeting, Chicago, Ill,

Comparison of histopathologic–clinical characteristics of Jessner's lymphocytic infiltration of the skin and lupus erythematosus tumidus: Multicenter.

Circumscribed palmar hypokeratosis

Facial pilomatrix carcinomas treated with Mohs micrographic surgery

Analysis of the lymphatic vessel architecture of atypical fibroxanthoma and pleomorphic dermal sarcoma Carolin Zschoche, MD, Corinna Hamsch, MD, Heinz.

Umbilical endometriosis elucidates cause of recurrent pneumothorax

Expression of PD-L1 in mastocytosis

Keratoacanthomas associated with sorafenib therapy

Idiopathic eruptive macular pigmentation associated with pregnancy and Hashimoto thyroiditis Danica Milobratovic, MD, Sanja Djordjevic, MD, Jelica Vukicevic,

Diffuse depigmentation in a patient with chronic myeloid leukemia

Penile sebaceous adenoma

Exploring the relationship between natural killer cells and cutaneous squamous cell carcinoma development Muneeb Ilyas, BSc, Collin M. Costello, BS,

Negative results of patch testing with standard and textile series in a case of annular lichenoid dermatitis of youth Carlos de la Torre, MD, PhD, Ángeles.

Pigmentation after using topical tacrolimus to treat lichen sclerosus: Possible role of stem cell factor Young Jin Kim, MD, Hee Young Kang, MD, PhD

Easwar Natarajan, BDS, DMSc, Sook-Bin Woo, DMD

Cholangiocarcinoma with skin metastases

Mid-dermal elastolysis as a manifestation of immune reconstitution inflammatory syndrome in an HIV-infected patient Carlo Cota, MD, Alessandra Latini,

Pink pigtails are a clue for the diagnosis of scabies

Volume 1, Issue 4, Pages (July 2015)

A definitive case of metastatic folliculotropic melanoma

Serkan Demirkan, MD, Özgür Gündüz, MD, Tuba Devrim, MD

Disseminated superficial porokeratosis involving the groin and genitalia in a 72-year-old immunocompetent man Laura Gray Pruitt, BS, Ling-Lun Bob Hsia,

Digital metastasis of tongue squamous cell carcinoma

Myiasis in a giant squamous cell carcinoma

Median raphe cyst on the scrotum and perineum

Scleroderma-like changes in cutaneous eruption of rhabdomyolysis

Third-trimester impetigo herpetiformis treated with cyclosporine

Extragenital condyloma acuminatum in the left axillary vault

Brooke T. Baldwin, BS, Amy Prakash, MD, Neil A. Fenske, MD, Jane L

Congenital hypertrichotic melanoneurocytoma: A congenital hypertrichotic plaque with overlapping neural and nevoid features Gene H. Kim, MD, Pedram Gerami,

Scott M. Peters, DDS, Louis Mandel, DDS, Michael A. Perrino, DDS, MD

A case of acrodermatitis enteropathica-like dermatosis caused by ornithine transcarbamylase deficiency∗ Jeong-Yeob Lee, MD, Sung-Eun Chang, MD, Chi-Woo.

A rare variant of porokeratosis: Porokeratosis ptychotropica

Jennifer Nicole Harb, MD, Kiran Motaparthi, MD JAAD Case Reports

Localized nephrogenic fibrosing dermopathy: Aberrant dermal repairing?

Volume 3, Issue 4, Pages (July 2017)

Solomon Shockman, MD, Lauren Krug, MD, Nektarios Lountzis, MD

Cutaneous sarcoidosis and primary biliary cirrhosis: A chance association or related diseases? Sowmya Kishor, MD, Maria L. Turner, MD, Brian B. Borg,

Alternating histopathologic pattern in blaschkoid dermatoses with epidermal changes: A retrospective series of 61 cases Vishal Gupta, MD, Sujay Khandpur,

Volume 4, Issue 6, Pages (July 2018)

The pathophysiologic basis of scabietic nodules

Spectrum and progression of disease from condyloma to aggressive anogenital squamous cell carcinoma in 3 HIV-positive patients Olaf Rodriguez, BS, Carrie.

Volume 4, Issue 3, Pages (April 2018)

Late-onset solitary porokeratotic eccrine ostial and dermal duct nevus

Integrating clinical, dermoscopy, and reflectance confocal microscopy findings into correctly identifying a nevoid melanoma Manu Jain, MD, Ashfaq A.

New-onset acrokeratoelastoidosis in an immunosuppressed patient

A case of congenital erosive and vesicular dermatosis with limited involvement Ji Hyun Lee, MD, Sun Young Yoon, MD, Jeong Deuk Lee, MD, Sang Hyun Cho,

A pink and purple plaque

Multisystemic Langerhans cell histiocytosis in an adult

Dermoscopic appearance of dermatofibroma-like Spitz nevus

Penile condylomata? Traumatic neuromas!

Quiz Page January 2010 American Journal of Kidney Diseases

Violaceous plaque on the forehead clinically resembling angiosarcoma: Cutaneous metastasis in a patient with prostatic adenocarcinoma John S. Boswell,

PUVA therapy in necrobiosis lipoidica diabeticorum

A subcutaneous nodule on the mid back

Importance of keen observation for the diagnosis of epidermal cysts: Dermoscopy can be a useful adjuvant tool Je-Ho Mun, MD, Sung-Min Park, MD, Tae-Wook.

Black dots in palmoplantar warts—challenging a concept: A histopathologic study Isabella Fried, MD, Romano Silvio Kasper, MD, Ivan Hegyi, MD, Werner Kempf,

Topically applied ascorbic acid solution for the treatment of basal cell carcinoma (BCC) Péter Holló, MD, PhD, Hajnalka Jókai, MD, PhD, Judit Hársing,

Volume 2, Issue 3, Pages (May 2016)

Volume 5, Issue 6, Pages (June 2019)

Presentation transcript:

Circumscribed palmar or plantar hypokeratosis: A distinctive epidermal malformation of the palms or soles Amparo Pérez, MDa, Arno Rütten, MDb, Reinhard Gold, MDc, Francisco Urbina, MDd, Carlos Misad, MDd, Maria José Izquierdo, MDe, Celia Requena, MDa, Adolfo Aliaga, MDa, Heinz Kutzner, MDb, Luis Requena, MDe Journal of the American Academy of Dermatology Volume 47, Issue 1, Pages 21-27 (July 2002) DOI: 10.1067/mjd.2002.120466 Copyright © 2002 American Academy of Dermatology, Inc Terms and Conditions

Fig. 1 Clinical appearance of lesions. A, Case 1. B, Case 6. C, Case 3. D, Case 2. Journal of the American Academy of Dermatology 2002 47, 21-27DOI: (10.1067/mjd.2002.120466) Copyright © 2002 American Academy of Dermatology, Inc Terms and Conditions

Fig. 2 Histopathologic features in case 6. A, Depression of epidermis, with sharp stair in horny layer between normal and involved skin. B, Epidermis covering depression showed thinner horny and granular cell layers when compared with adjacent noninvolved skin. C, Corneocytes of border of stair appeared frayed and more eosinophilic than adjacent normal basophilic corneocytes. (Hematoxylin-eosin stain; original magnifications: A, ×20; B, ×100; C, ×200.) Journal of the American Academy of Dermatology 2002 47, 21-27DOI: (10.1067/mjd.2002.120466) Copyright © 2002 American Academy of Dermatology, Inc Terms and Conditions

Fig. 3 Histopathologic features in case 4. A, Stair of transition between normal and thin horny layer seems to be related with an acrosyringium, but this could not be demonstrated in other cases. Furthermore, acrosyringium crossing area of depressed epidermis (arrow) was also involved because it showed thinner horny layer than normal adjacent acrosyringia. B, Epidermis in depressed area showed thinner granular and horny layers than did adjacent normal skin. C, Higher magnification demonstrated absence of cornoid lamella at stair of depression of horny layer. (Hematoxylin-eosin stain; original magnifications: A, ×20; B, ×100; C, ×200.) Journal of the American Academy of Dermatology 2002 47, 21-27DOI: (10.1067/mjd.2002.120466) Copyright © 2002 American Academy of Dermatology, Inc Terms and Conditions

Fig. 4 Histopathologic study of case of porokeratosis of Mibelli involving palmar skin. A, Low-power magnification showed depression of epidermis with sharp transition between normal and involved skin. B, Higher magnification, showed keratin-filled invagination at peripheral ridge of lesion, from which emerged parakeratotic column, “cornoid lamella.” C, In epidermis beneath this cornoid lamella, there was no granular layer; pyknotic keratinocytes and dyskeratotic cells were irregularly arranged. (Hematoxylin-eosin stain; original magnifications: A, ×20; B, ×100; C, ×200.) Journal of the American Academy of Dermatology 2002 47, 21-27DOI: (10.1067/mjd.2002.120466) Copyright © 2002 American Academy of Dermatology, Inc Terms and Conditions