H. Zhang, M. D. , Ph. D. , K. W. Marshall, M. D. , Ph. D. , F. R. C. S

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Profiling genes expressed in human fetal cartilage using 13,155 expressed sequence tags H. Zhang, M.D., Ph.D., K.W. Marshall, M.D., Ph.D., F.R.C.S. (C), H. Tang, M.Sc., D.M. Hwang, M.D., Ph.D., M. Lee, B.Sc., C.C. Liew, Ph.D. Osteoarthritis and Cartilage Volume 11, Issue 5, Pages 309-319 (May 2003) DOI: 10.1016/S1063-4584(03)00032-3

Fig. 1 Relative expression levels of seven types of ECM proteins in human fetal cartilage. EST numbers matched to each type of ECM were summed. EST frequency was then calculated by dividing the EST copy number of each ECM into the total number of ECM ESTs (n=1056). COL, collagens; PG, proteoglycans; MATN1, matrilin 1; SPARC, secreted protein, acidic and rich in cysteine (osteonectin); CRTL1, cartilage link protein 1; FN, fibronectin. Osteoarthritis and Cartilage 2003 11, 309-319DOI: (10.1016/S1063-4584(03)00032-3)

Fig. 2 Relative expression levels of nine collagen genes in human fetal cartilage. Relative EST frequency level was calculated by dividing the EST copy number of each collagen gene into the total number of collagen ESTs (n=723). Osteoarthritis and Cartilage 2003 11, 309-319DOI: (10.1016/S1063-4584(03)00032-3)

Fig. 3 Relative expression levels of six proteoglycan genes in human fetal cartilage. Relative EST frequency level was calculated by dividing the EST copy number of each proteoglycan gene into the total number of proteoglycan ESTs (n=92). GPC3, glypican 3; DCN, decorin; AGG, aggrecan; PG4, proteoglycan 4; LUM, lumican; SDC2, syndecan 2; FMOD, fibromodulin. Osteoarthritis and Cartilage 2003 11, 309-319DOI: (10.1016/S1063-4584(03)00032-3)