Reduced Left Ventricular Compacta Thickness: A Novel Echocardiographic Criterion for Non-Compaction Cardiomyopathy Catherine Gebhard, MD, Barbara E.

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Reduced Left Ventricular Compacta Thickness: A Novel Echocardiographic Criterion for Non-Compaction Cardiomyopathy Catherine Gebhard, MD, Barbara E. Stähli, MD, Matthias Greutmann, MD, Patric Biaggi, MD, Rolf Jenni, MD, MSEE, Felix C. Tanner, MD Journal of the American Society of Echocardiography Volume 25, Issue 10, Pages 1050-1057 (October 2012) DOI: 10.1016/j.echo.2012.07.003 Copyright © 2012 American Society of Echocardiography Terms and Conditions

Figure 1 Representative example of echocardiographic measurements in the parasternal short-axis view in a patient with LVNC (A) compared with one with AVS (B). C, compacted myocardial layer; N, noncompacted myocardial layer. Journal of the American Society of Echocardiography 2012 25, 1050-1057DOI: (10.1016/j.echo.2012.07.003) Copyright © 2012 American Society of Echocardiography Terms and Conditions

Figure 2 Three-dimensional full-volume acquisition of the left ventricle. (A) Measurement of left ventricular wall thickness at the midventricular level in a transverse plane placed perpendicular to the ventricular long axis. (B) Measurement of left ventricular wall thickness at the midventricular level in a transverse plane tilted by 20° relative to the ventricular long axis. Journal of the American Society of Echocardiography 2012 25, 1050-1057DOI: (10.1016/j.echo.2012.07.003) Copyright © 2012 American Society of Echocardiography Terms and Conditions

Figure 3 (A) Bar graph comparing left ventricular ejection fraction (LV-EF) in patients with LVNC versus controls and patients with AVS (∗P < .001). (B) Bar graph comparing left ventricular end-diastolic diameter (LVEDD) in patients with LVNC versus controls and patients with AVS (∗P < .001). (C) Bar graph comparing septal wall thickness in patients with LVNC versus controls and patients with AVS (∗P < .0001). (D) Bar graph comparing indexed septal wall thickness in patients with LVNC versus controls and patients with AVS (∗P < .0001). Journal of the American Society of Echocardiography 2012 25, 1050-1057DOI: (10.1016/j.echo.2012.07.003) Copyright © 2012 American Society of Echocardiography Terms and Conditions

Figure 4 (A) Scatterplot comparing the ratio of indexed basal septal wall thickness (M-mode) to compacta thickness in patients with LVNC versus controls and patients with AVS. (B) Scatterplot comparing the ratio of indexed basal septal wall thickness (2D) to compacta thickness in patients with LVNC versus controls and patients with AVS. (C) Scatterplot comparing the ratio of indexed midventricular septal wall thickness (2D) to compacta thickness in patients with LVNC versus controls and patients with AVS. Journal of the American Society of Echocardiography 2012 25, 1050-1057DOI: (10.1016/j.echo.2012.07.003) Copyright © 2012 American Society of Echocardiography Terms and Conditions

Figure 5 (A) Scatterplot comparing total wall thickness in patients with LVNC versus controls and patients with AVS. (B) Scatterplot comparing the ratio of noncompacta to compacta in patients with LVNC versus controls and patients with AVS. Journal of the American Society of Echocardiography 2012 25, 1050-1057DOI: (10.1016/j.echo.2012.07.003) Copyright © 2012 American Society of Echocardiography Terms and Conditions

Figure 6 (A) Scatterplot comparing the thickness of noncompacta in patients with LVNC versus controls and patients with AVS. (B) Scatterplot comparing the thickness of compacta in patients with LVNC versus controls and patients with AVS. Journal of the American Society of Echocardiography 2012 25, 1050-1057DOI: (10.1016/j.echo.2012.07.003) Copyright © 2012 American Society of Echocardiography Terms and Conditions