Poor glycemic control and decreased renal function are associated with increased intrarenal RAS activity in Type 2 diabetes mellitus S. Nakatani, E.

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Poor glycemic control and decreased renal function are associated with increased intrarenal RAS activity in Type 2 diabetes mellitus S. Nakatani, E. Ishimura, T. Naganuma, A. Nakatani, M. Ichii, S. Fukumoto, K. Mori, M. Emoto, T. Nakatani, M. Inaba Diabetes Research and Clinical Practice Volume 105, Issue 1, Pages 40-46 (July 2014) DOI: 10.1016/j.diabres.2014.04.019 Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions

Fig. 1 Investigation of Log (urinary [angiotensinogen:creatinine]) (Log(UAGT/Ucre)) in patients with type 2 diabetes mellitus without nephropathy. Age, hemoglobin A1c (HbA1c), and fasting plasma glucose (FPG) correlated significantly and positively with Log (UAGT/Ucre) ((A)–(C), respectively). Diabetes Research and Clinical Practice 2014 105, 40-46DOI: (10.1016/j.diabres.2014.04.019) Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions

Fig. 2 Investigation of Log(urinary [angiotensinogen:creatinine]) (Log(UAGT/Ucre)) in patients with type 2 diabetes mellitus and chronic kidney disease. Systolic blood pressure (SBP), serum creatinine, and urinary [albumin:creatinine] (UACR) correlated significantly and positively with Log (UAGT/Ucre) ((A)–(C), respectively). Estimated glomerular filtration rate (eGFR) correlated significantly and inversely with the Log (UAGT/Ucre) (D). Diabetes Research and Clinical Practice 2014 105, 40-46DOI: (10.1016/j.diabres.2014.04.019) Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions