The VERITY Steering Committee Third Venous Thromboembolism Registry Report 2005

Schematic of the report production process

List of contributors

List of contributors

List of contributors

Example table

Number of risk factors for patients with VTE (n=4,603)

Overview

Database overview

The growth of the database (n=27,179)

Data submitted by each centre

Number of risk factors and diagnosis

Number of risk factors for patients with VTE (n=4,603)

Final diagnosis and the number of risk factors (n=17,175)

Age distribution for all patients with VTE (n=27,123)

Final diagnosis over time (n=21,486)

Age and gender for patients with VTE

Age and gender for patients with VTE (n=6,045)

Age and gender for patients with VTE and Cancer (n=799)

Rates of different risk factors in patients who have VTE

Presence of various risk factors and final diagnosis

Task Force of the British Committee for Standards in Haematology13

D-dimer result and final diagnosis

Final diagnosis and D-dimer test (n=16,005)

D-dimer result, DVT pre-test probability and final diagnosis

Final diagnosis, D-dimer result, D-dimer test and DVT pre-test probability (n=11,585)

Suitability for home treatment1 amongst patients with confirmed DVT (n=5,371)

Reason patients with DVT were deemed unsuitable for home treatment; (patients unsuitable for home treatment with recorded reason n=466)

Duration of LMWH therapy and time to therapeutic INR in patients with DVT; patients receiving both treatments only (n=3,248)

Kaplan-Meier survival curves for patients with confirmed diagnosis of DVT and PE (n=2,224)

Pulmonary embolism

Primary and final diagnosis

Numbers of risk factors

Number of risk factors according to final diagnosis (n=4,603)

Different risk factors

Presence of selected risk factors for PE and non-PE patients

Age and disease

Age distributions according to final diagnosis (n=6,115)

A. Management of suspected non-massive pulmonary A. Management of suspected non-massive pulmonary embolism with isotope lung scanning off site only

B. Management of suspected non-massive pulmonary B. Management of suspected non-massive pulmonary embolism with isotope lung scanning available on site

PTP score and final diagnosis

PTP score distributions for patients with confirmed PE and non-PE patients (n=279 and n=342 respectively)

PTP score distributions for patients with confirmed PE and non-PE patients (n=279 and n=342 respectively)

PTP score D-dimer and final diagnosis

Using <4 and ≥4 to classify the PE PTP score Final diagnosis, D-dimer results and PE PTP score for patients with a suspected PE (n=438) Using <4 and ≥4 to classify the PE PTP score

Using <2,2-6 and >6 to classify the PE PTP score Final diagnosis, D-dimer results and PE PTP score for patients with a suspected PE (n=438) Using <2,2-6 and >6 to classify the PE PTP score

Other investigations performed

Investigations performed and diagnosis

Chest x-ray

The Royal Perth Hospital algorithm

Treatment of patients with PE – location of treatment

Suitability of PE patients for home treatment1 (n=457)

Doses of LMWH

Average number of doses of LMWH for non-PE and PE patients; bars denote standard error

Prediction of the risk of adverse events in PE patients

Thromboprophylaxis

Source of referral for medical inpatients with VTE

Source of referral for surgical inpatients with VTE

Source of referral for patients with a history of surgical inpatient stay and VTE (n=685)

Final diagnosis and inpatient history - Overview

Final diagnosis and inpatient history

Focus on medical inpatient history

Medical inpatient history for each final diagnosis (n=21,080)

Focus on surgical inpatient history

Surgical inpatient history for each final diagnosis (n=20,996)

Speciality for VTE patients who have recently had surgery (n=685)

Thromboprophylaxis provision for VTE patients (n=3,189)

Source of referral and the use of thromboptophylaxis for VTE patients (n=3,580)

Trends in the use of LMWH as thromboprophylasis for VTE patients (n=730)

Thromboprophylaxis and surgical speciality for VTE patients

Thromboprophylaxis provision and surgical speciality for VTE patients (n=603)

Thromboprophylaxis and inpatient stay

Type of thromboprophylaxis, final diagnosis and inpatient history

Thromboprophylaxis and risk factors in medical inpatients with VTE

Final diagnosis and new risk score

Final diagnosis of VTE and weighted risk score (n=5,692)

Thromboprophylaxis and the weighted score

Thromboprophylaxis and weighted risk score (n=4,794)

Kaplan-Meier survival curves for patients with confirmed diagnoses of DVT according to recent medical inpatient history (n=242 and n=1,883 respectively)

Kaplan-Meier survival curves for patients with confirmed diagnoses of DVT according to recent surgical inpatient history (n=266 and n=1,839 respectively)

Number of referrals over time according to patients’ history and Percentage of patients with confirmed VTE over time according to patients’ history

Number of referrals over time according to patients’ history and Percentage of patients with confirmed VTE over time according to patients’ history

VTE and Cancer

Cancer rates amongst VTE patients at each hospital

Final diagnosis and cancer

Presence of a final diagnosis of VTE in cancer and non-cancer patients

Cancer, age and gender in patients with VTE

Cancer rates broken down by age and gender for patients with VTE (n=5,655)

Specific type of cancer and age for patients with VTE

Specific type of cancer and age for patients with VTE

Cancer rates broken down by age for the most frequently occuring cancers in VERITY amongst patients with VTE (n=5,582)

Specific type of cancer and final diagnosis

Type of cancer and final diagnosis (n=1,205)

D-dimer and cancer

D-dimer results in the context of cancer (n=15,240)

Location of treatment

Location of treatment and cancer for VTE patients (n=5,480)

Doses of LMWH

Duration of LMWH therapy and time to therapeutic INR in patients with DVT in the context of cancer; patients receiving both therapies only (n=3,444)

Duration of LMWH therapy in patients with VTE in the context of cancer (n=4,138)

Kaplan-Meier survival curves for patients with confirmed diagnoses of VTE according to the presence of absence of cancer (n=2,224)

Walsgrave hospital: Cancer and medium-term mortality in VTE patients

VTE and Pregnancy

Final diagnosis and pregnancy

Final diagnosis and pregnancy (n=12,336)

Risk factors and pregnancy

Final diagnosis and pregnancy (n=3,389)

Final diagnosis and selected risk factors amongst pregnant patients

Investigations and pregnancy

Investigations in pregnant patients

Treatment and pregnancy – use of LMWH

LMWH use and final diagnosis for pregnant patients (n=378)

Doses of LMWH

LMWH doses and final diagnosis for pregnant patients; bars denote standard errors (n=89 and 50 respectively)

Warfarin therapy and post partum

Warfarin use and final diagnosis for post partum patients (n=425)

Summary of protocol for thromboprophylaxis in women with previous VTE and / or thrombophiliai

A clinical model for predicting pre-test probability for deep vein thrombosisi

Variables used to determine a pre-test probability score in patients with suspected pulmonary embolismii

A new weighted score to determine the risk of VTEiii