Assist. Prof. Dr. Açelya Yılmazer Aktuna Cell Biology BME140 Lecture 9 Cell Cycle Assist. Prof. Dr. Açelya Yılmazer Aktuna
CELL CYCLE Signal transduction Change in gene expression Steps in cell cycle: Signal transduction Change in gene expression Activation of Cyclin/CDK complexes (START) Phosphorylation of pocket proteins (E2F) DNA replication
CELL CYCLE Passing S phase checkpoints Increase in cell size (G2) Steps in cell cycle: Passing S phase checkpoints Increase in cell size (G2) Entry to M phase Chromosome alignment during M phase Cytokinesis
APOPTOSIS & NECROSIS Cells Die in Two Different Ways: Necrosis and Apoptosis Apoptosis Is Induced via at Least Two Different Pathways