Assist. Prof. Dr. Açelya Yılmazer Aktuna

Slides:



Advertisements
Similar presentations
Fundamentals of Cell Biology Chapter 13: The Birth and Death of Cells
Advertisements

Cell Division and Apoptosis II chapter 17. Activation of a cyclin dependent kinase.
Zoo-352 Principles of genetics Lecture 3 The cell cycle and its checkpoints.
1 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Chapter 18 Patterns of Chromosome Inheritance Lecture Outline.
1 hr hr 8 hr 4-6 hr (M) Spindle-assembly checkpoint - confirms that all the chromosomes are properly attached to the spindles. Resting phase (G0)
Cell & Molecular Biology Control of the Cell Cycle.
The Cell Cycle Day 3. Cancer: Out of Control Cell Division The defining feature of a cancerous cell is that is divides much more often than is healthy-
Cancer. Regulation of Cell Division Two sets of genes control cell division. –Proto-oncogenes. Code for proteins that promote the cell cycle and prevent.
Genetics of Cancer Genetic Mutations that Lead to Uncontrolled Cell Growth.
G 1 and S Phases of the Cell Cycle SIGMA-ALDRICH.
Cell Cycle Stages cells pass through from 1 cell division to the next.
CELL CYCLE Cell Growth  Body cells spend most of its life growing and doing work. But it can only grow so large.  Body cells consist of skin,
Cell Cycle The cell cycle describes the fate of body (somatic) cells There are distinct stages to the cell cycle – Interphase… preparing for Mitosis Replication.
Lesson Overview Lesson Overview The Process of Cell Division Cell Division.
G2 Checkpoint 1.Controls entry to mitosis 2. DNA replication assessed 3. Full genome must be present to allow copy for each daughter cell M-checkpoint.
AH Biology: Unit 1 Control of the Cell Cycle. The cell cycle: summary G1G1 G2G2 S Interphase M Cytokinesis Mitosis.
Tests back Chapter 11. No Distance Short Distance Long Distance.
Normal cell cycle DNA replication Doughter cells G2 phase Nuclear division Cytokinesis 1x.
Lecture 10: Cell cycle Dr. Mamoun Ahram Faculty of Medicine
Cell Cycle Regulation. The Cell Cycle What can be learned from this experiment? There are different signals (proteins) present that aid in the progression.
Mitosis Lab. Interphase
Cell Division. Paired “threads” Figure 8.1 An Early View of Mitosis.
8.1 CELL DIVISION AND CELL CYCLE PAGES The Cell Cycle.
Negative regulation of cell cycle by intracellular signals Checkpoint p53 detects DNA damage & activates p21 p21 inhibits cdk2-cyclinA Intracellular Regulation.
The Cell Cycle and Cancer. How is growth controlled? How is the Cell Cycle Regulated? Clue: cytoplasmic chemicals can signal mitosis.
Cell Cycle Regulation Chapter – Pt. 1 Pgs Objective: I can describe and how the cell cycle is regulated and controlled to occur at certain.
The blue circle marks the position of a vital checkpoint in cell cycle control. What would the consequence of a malfunction at this checkpoint? A.
CANCER MODULE Units 1.3, 2.2, 2.3, 2.4, 2.5. REGULATION OF THE CELL CYCLE Drivers Checkpoints Divide!!Don’t divide!!
1 The Cell Cycle “Mitosis” Packet #33 Chapter #13 Friday, November 18, 2016.
Biology 205 Lecture 06: Mitosis and the cell cycle (and some meiosis review) Readings DO NOT POST THESE LECTURES!!! INSTRUCTOR VERSIONS.
Chapter 9 Cell Cycle and Cancer. Figure 17-1 Molecular Biology of the Cell (© Garland Science 2008) Cell Cycle.
Lecture 35 Normal Cell Cycle Ozgur Unal
Assist. Prof. Dr. Açelya Yılmazer Aktuna
Cell cycle 김다은 성균관대학교 / 약학과
Discuss with your neighbor, how you started as one cell and are now made up of over 3 trillion cells.
Control of Gene Expression
Chapter 11 Replication Is Connected to the Cell Cycle
Cell Biology BME140 Structural and functional analysis of nucleus and nuclear compartments Assist. Prof. Dr. Açelya Yılmazer Aktuna.
The Cell Cycle and Mitosis
Pre – AP Biology The Cell Cycle (1.5) Part 1.
محاضرة عامة التقنيات الحيوية (هندسة الجينات .. مبادئ وتطبيقات)
Cells Alive – Cell Cycle
Cell Cycle & Checkpoints
Chapter 12: The Cell Cycle
Regulation of mesangial cell proliferation
BIOLOGY 12 Cancer.
Regulation of Gene Expression
Is Hepatitis C Virus Carcinogenic?
Chapter 12: The Cell Cycle
Chapter 12: The Cell Cycle
The Cell Cycle and Cell Division
Cancer and the Cell Cycle
Sponge Explain the process of mitosis in your own words.
Cell Communication (Signaling) Part 3
AP Biology The Cell Cycle.
Pre – AP Biology The Cell Cycle (1.5) Part 1.
Cytokinesis & Control Over Cell Division
Cell Cycle Regulation Learning Activities
CHAPTER 11 GENETICS Genetics is the study of how traits or characteristics are inherited. Inherited characteristics are controlled by genes and are passed.
Cell Communication (Signaling) Part 3
Cell Biology BME140 Lecture 9 Signal Transduction Pathways
Chapter 12: The Cell Cycle
Control of the Cell Cycle
Chapter 12: The Cell Cycle
Cell Biology BME140 Lecture 1 Diversity of Cells and Main Features
Loss of Drp1 induces replication stress-mediated genome instability.
Phases of the Cell Cycle
Phases of the Cell Cycle
The cell cycle and RB The cell cycle and RB The cell cycle is depicted, showing the phases (divided by chevrons): growth or gap 1 (G1), DNA synthesis (S),
Presentation transcript:

Assist. Prof. Dr. Açelya Yılmazer Aktuna Cell Biology BME140 Lecture 9 Cell Cycle Assist. Prof. Dr. Açelya Yılmazer Aktuna

CELL CYCLE Signal transduction Change in gene expression Steps in cell cycle: Signal transduction Change in gene expression Activation of Cyclin/CDK complexes (START) Phosphorylation of pocket proteins (E2F) DNA replication

CELL CYCLE Passing S phase checkpoints Increase in cell size (G2) Steps in cell cycle: Passing S phase checkpoints Increase in cell size (G2) Entry to M phase Chromosome alignment during M phase Cytokinesis

APOPTOSIS & NECROSIS Cells Die in Two Different Ways: Necrosis and Apoptosis Apoptosis Is Induced via at Least Two Different Pathways