Relation of Heart Rate at Rest and Long-Term (>20 Years) Death Rate in Initially Healthy Middle-Aged Men  Xavier Jouven, MD, PhD, Jean Philippe Empana,

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Presentation transcript:

Relation of Heart Rate at Rest and Long-Term (>20 Years) Death Rate in Initially Healthy Middle-Aged Men  Xavier Jouven, MD, PhD, Jean Philippe Empana, MD, PhD, Sylvie Escolano, PhD, Jean François Buyck, MD, Muriel Tafflet, PhD, Michel Desnos, MD, Pierre Ducimetière, PhD  American Journal of Cardiology  Volume 103, Issue 2, Pages 279-283 (January 2009) DOI: 10.1016/j.amjcard.2008.08.071 Copyright © 2009 Elsevier Inc. Terms and Conditions

Figure 1 Hazard ratios and 95% CIs in univariate analysis and after adjustments for age, tobacco consumption, current sport activity, diabetes, body mass index, systolic blood pressure, and cholesterol. The second tertile is the reference (ref) group. bpm = beats per minute. American Journal of Cardiology 2009 103, 279-283DOI: (10.1016/j.amjcard.2008.08.071) Copyright © 2009 Elsevier Inc. Terms and Conditions

Figure 2 Survival curves of follow-up in the Paris Prospective Study 1 over 20 years are Kaplan-Meier estimates for the 3 × 3 tertile groups of baseline HR and HR change after 5 years of follow-up. American Journal of Cardiology 2009 103, 279-283DOI: (10.1016/j.amjcard.2008.08.071) Copyright © 2009 Elsevier Inc. Terms and Conditions

Figure 3 RRs of global mortality according to HR at rest at inclusion and HR change after 5 years after adjustment for the usual risk factors. The central group (i.e., tertile 2 for both variables) is the reference. Tertiles of baseline HR are defined as low (<64 beats/min), medium (64 to 70 beats/min), and high HR (>70 beats/min). Tertiles of HR change are tertile 1, decrease >4 beats/min; tertile 2, −4 to +3 beats/min; and tertile 3, increase >3 beats/min. American Journal of Cardiology 2009 103, 279-283DOI: (10.1016/j.amjcard.2008.08.071) Copyright © 2009 Elsevier Inc. Terms and Conditions