An update on European Paediatric Formulation Initiative (EuPFi)

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Presentation transcript:

An update on European Paediatric Formulation Initiative (EuPFi) Dr Catherine TULEU Reader, Department of Pharmaceutics & Director, Centre for Paediatric Pharmacy Research Age Related Medicines Focus Group meeting - Monday 30th September

CPPR Centre for Paediatric Pharmacy Research Parents Carers Formulation Medicines Child Safety Prescribers Since 2002 (Prof IK Wong) PK/PD PG Dr Joseph Standing (ICH/GOSH) Dr Yogini Jani (UCLH) Dr Tuleu (director) MCRN P&P CSG (2005-) FWG PDCO external expert (2007-) PEAG MHRA (2010-) EuPFi Chair (2007-) FP7 Network of excellence (2011-2016 ) RA, PhD, Mres, MSc, Visiting & Erasmus, Mpharm students Drug utilisation Dr Macey Murray Compliance Adherence Concordance Pharmaco-epidemiology www.ucl.ac.uk/pharmacy/people/PracticeandPolicy/dpp_research_centres/paediatric_pharmacy_research

European Paediatric Formulation Initiative objectives Identify the issues and challenges associated with development of paediatric formulation and consider ways towards better medications and clinically relevant dosage forms for children Promote early pharmaceutical consideration for development of paediatric medicines. Identify potential information, knowledge, know-how gaps in the paediatric formulation development. Improve the availability of information of paediatric formulations. Raising awareness (publications, conferences etc.) Linking and networking Quick fact: Non profit organisation Core management group Members from industry, academia, hospital and regulatory agencies dedicated to fulfilling its mission. Established in London in 2007. Membership open to anyone interested in paediatric formulation development. 5 Workstreams Annual Conferences

EuPFI members SPONSORS OBSERVER Mission To promote and facilitate preparation of better & safe medicines for children through Sharing expertise and interactive discussion between industry, academia, clinical and regulatory professionals. Information dissemination USA -Eunice Kennedy Shriver National Institute of Child Health and Human Development Pediatrics Formulation Initiative I-Q consortium

Accepted for publication Accomplishments WS 1 WS 2 WS 3 WS4 WS5 Administration Devices Modification of Dosage Forms Required for Children (MDFRC) Taste Masking and Taste Testing Age Appropriateness of Formulations Pharmaceutical Excipients Accepted for publication Submitted to ADDR

Formulating better medicines for children 1st conference with APS 2009, LONDON 100 participants Formulating better medicines for children 6th conference 17th to 18th September 2014 Athens, Greece 150-200 participants