Presented By James Hill at 2016 ASCO Annual Meeting

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Presentation transcript:

Presented By James Hill at 2016 ASCO Annual Meeting The CREST Trial Presented By James Hill at 2016 ASCO Annual Meeting

Learning Objectives for obstructing colorectal cancer Presented By James Hill at 2016 ASCO Annual Meeting

Rationale of CREST – Converting emergency into elective surgery Presented By James Hill at 2016 ASCO Annual Meeting

Presented By James Hill at 2016 ASCO Annual Meeting Self-expandable metal stents for obstructing colonic and extracolonic cancer: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline - Endoscopy 2014; 46: 990–1002 Presented By James Hill at 2016 ASCO Annual Meeting

CREST – Primary Objectives Presented By James Hill at 2016 ASCO Annual Meeting

CREST – Secondary outcome measures Presented By James Hill at 2016 ASCO Annual Meeting

Presented By James Hill at 2016 ASCO Annual Meeting The CREST Trial Design Presented By James Hill at 2016 ASCO Annual Meeting

CREST – Eligibility Criteria Presented By James Hill at 2016 ASCO Annual Meeting

Compliance with Randomised Treatment Allocation Presented By James Hill at 2016 ASCO Annual Meeting

CREST Patient Demographics Presented By James Hill at 2016 ASCO Annual Meeting

CREST Patient Baseline Data Presented By James Hill at 2016 ASCO Annual Meeting

CREST Patient Baseline Data - Stratification Presented By James Hill at 2016 ASCO Annual Meeting

Does stenting reduce length of stay and 30-day mortality? Presented By James Hill at 2016 ASCO Annual Meeting

Stenting Completion and Immediate Complication Rate Presented By James Hill at 2016 ASCO Annual Meeting

Stenting Intermediate and Late Complication Rates Presented By James Hill at 2016 ASCO Annual Meeting

Stent related perforations Presented By James Hill at 2016 ASCO Annual Meeting

Does stenting reduce stoma rates? Presented By James Hill at 2016 ASCO Annual Meeting

Presented By James Hill at 2016 ASCO Annual Meeting 6-Month Survival Rates Presented By James Hill at 2016 ASCO Annual Meeting

Severity of Surgical Complications (Clavien-Dindo Classification) Presented By James Hill at 2016 ASCO Annual Meeting

Presented By James Hill at 2016 ASCO Annual Meeting Summary Presented By James Hill at 2016 ASCO Annual Meeting

Conclusions – SEMS as a bridge to surgery Presented By James Hill at 2016 ASCO Annual Meeting