Correlation between Optical Coherence Tomography and Fluorescein Angiography Findings in Diabetic Macular Edema  Tomohiro Otani, MD, Shoji Kishi, MD  Ophthalmology  Volume 114, Issue 1, Pages 104-107 (January 2007) DOI: 10.1016/j.ophtha.2006.06.044 Copyright © 2007 American Academy of Ophthalmology Terms and Conditions

Figure 1 Patient 2. The late-phase fluorescein angiogram (A) shows cystoid hyperfluorescence, with a petalloid pattern in the foveal area (small circle) and honeycomb pattern in the perifoveal area (large circle), except in the nasal and inferonasal portions. Optical coherence tomography scans (B, C) show that the central fovea has cystic spaces (white asterisk). The perifoveal region with a honeycomb pattern of hyperfluorescence shows cystic spaces (arrowheads) in the inner nuclear layer (INL) and retinal swelling (yellow asterisks) in the OPL. The perifoveal region with no honeycomb pattern has retinal swelling (red arrow) in the OPL but no cystic changes in the INL. Ophthalmology 2007 114, 104-107DOI: (10.1016/j.ophtha.2006.06.044) Copyright © 2007 American Academy of Ophthalmology Terms and Conditions

Figure 2 Patient 3. The late-phase fluorescein angiogram (A) shows marked hyperfluorescence of the macula. In the foveal area (small circle), the hyperfluorescence appears petalloid, and in the perifoveal area (large circle), the configuration appears honeycombed. Optical coherence tomography scans (B, C) show large cystic spaces (white asterisks) in the foveal area. There are cystic changes (arrowheads) in the inner nuclear layer and retinal swelling (yellow asterisks) in the outer plexiform layer in the perifoveal regions. In the nasal and temporal perifoveal areas (B), there are cystic spaces (yellow arrows) in the innermost retinal layer. Ophthalmology 2007 114, 104-107DOI: (10.1016/j.ophtha.2006.06.044) Copyright © 2007 American Academy of Ophthalmology Terms and Conditions