Analysis of Macular Edema after Cataract Surgery in Patients with Diabetes Using Optical Coherence Tomography  Stephen J. Kim, MD, Robert Equi, MD, Neil.

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Analysis of Macular Edema after Cataract Surgery in Patients with Diabetes Using Optical Coherence Tomography  Stephen J. Kim, MD, Robert Equi, MD, Neil M. Bressler, MD  Ophthalmology  Volume 114, Issue 5, Pages 881-889 (May 2007) DOI: 10.1016/j.ophtha.2006.08.053 Copyright © 2007 American Academy of Ophthalmology Terms and Conditions

Figure 1 Top, Mean central point thickness and central subfield retinal thickness (micrometers) of study eyes preoperatively (pre-op) and 1 and 3 months after cataract surgery. Bottom, Representative range of cystoid abnormalities of study eyes with macular edema. Left, Preoperative optical coherence tomography (OCT). Right, One-month postoperative OCT. Ophthalmology 2007 114, 881-889DOI: (10.1016/j.ophtha.2006.08.053) Copyright © 2007 American Academy of Ophthalmology Terms and Conditions

Figure 2 Mean change in center point thickness (micrometers) from preoperative baseline at 1 and 3 months after surgery among study eyes grouped according to risk characteristics: non–insulin dependence (NIDDM) versus insulin dependence (IDDM), duration of diabetes < or ≥ 10 years, and by history of treated clinically significant macular edema (CSME). Ophthalmology 2007 114, 881-889DOI: (10.1016/j.ophtha.2006.08.053) Copyright © 2007 American Academy of Ophthalmology Terms and Conditions

Figure 3 Mean change in visual acuity (VA; logarithm of the minimum angle of resolution [logMAR]) from preoperative best-corrected VA at 1 and 3 months after surgery among study participants grouped according to risk characteristics: non–insulin dependence (NIDDM) versus insulin dependence (IDDM), duration of diabetes < or ≥ 10 years, and by history of treated clinically significant macular edema (CSME). *P = 0.007 at 1 month. Ophthalmology 2007 114, 881-889DOI: (10.1016/j.ophtha.2006.08.053) Copyright © 2007 American Academy of Ophthalmology Terms and Conditions

Figure 4 Mean change in center point thickness (micrometers) from preoperative measurements at 1 and 3 months after surgery among study participants with varying levels of diabetic retinopathy: none and mild (retinopathy that was mild and nonproliferative or less severe), all (any retinopathy, including mild, moderate, and severe nonproliferative, and proliferative), advanced (moderate nonproliferative, severe nonproliferative, proliferative). *P = 0.05 with reference to the none group at 1 and 3 months. Ophthalmology 2007 114, 881-889DOI: (10.1016/j.ophtha.2006.08.053) Copyright © 2007 American Academy of Ophthalmology Terms and Conditions

Figure 5 Mean change in visual acuity (VA; logarithm of the minimum angle of resolution [logMAR]) from preoperative best-corrected VA at 1 and 3 months after surgery among study participants with varying levels of diabetic retinopathy: none and mild (retinopathy that was mild nonproliferative or less severe), all (any retinopathy, including mild, moderate, and severe nonproliferative, and proliferative), advanced (moderate nonproliferative, severe nonproliferative, proliferative). *P = 0.08 with reference to the none group at 1 month. Ophthalmology 2007 114, 881-889DOI: (10.1016/j.ophtha.2006.08.053) Copyright © 2007 American Academy of Ophthalmology Terms and Conditions

Figure 6 Mean change in logarithm of the minimum angle of resolution (logMAR) visual acuity (VA) among study eyes with <30% and >30% increases in foveal thickness at 1 month (▨) and mean change in logMAR VA of the entire study group at 1 month (▩). *P<0.001, comparing mean change in logMAR VA between <30% and >30% groups. **P = 0.01, comparing mean change in logMAR VA between >30% group and study mean. Ophthalmology 2007 114, 881-889DOI: (10.1016/j.ophtha.2006.08.053) Copyright © 2007 American Academy of Ophthalmology Terms and Conditions

Figure 7 Mean center point thicknesses (micrometers) preoperatively (pre-op) and 1 and 3 months postoperatively of 11 study eyes that developed macular edema (ME) and 39 study eyes that did not develop macular edema. *P<0.001. Ophthalmology 2007 114, 881-889DOI: (10.1016/j.ophtha.2006.08.053) Copyright © 2007 American Academy of Ophthalmology Terms and Conditions

Figure 8 Mean change in logarithm of the minimum angle of resolution (logMAR) vision from preoperative best-corrected visual acuity at 1 and 3 months among study participants with macular edema (ME) (▨; 11 study eyes) and without ME (▩; 39 study eyes). *P>0.001. **P = 0.01. Ophthalmology 2007 114, 881-889DOI: (10.1016/j.ophtha.2006.08.053) Copyright © 2007 American Academy of Ophthalmology Terms and Conditions

Figure 9 Mean change in center point thickness (micrometers) from preoperative baseline at 1 and 3 months of eyes with a history of resolved clinically significant macular edema treated with or without intraoperative triamcinolone acetonide. N = no. of study eyes. *P = 0.03. **One study eye was lost to follow-up. Ophthalmology 2007 114, 881-889DOI: (10.1016/j.ophtha.2006.08.053) Copyright © 2007 American Academy of Ophthalmology Terms and Conditions

Figure 10 Mean change in logarithm of the minimum angle of resolution (logMAR) visual acuity (VA) from preoperative best-corrected VA at 1 and 3 months among eyes with a history of resolved clinically significant macular edema treated with or without intraoperative steroids. N = no. of study eyes. *One study eye was lost to follow-up. Ophthalmology 2007 114, 881-889DOI: (10.1016/j.ophtha.2006.08.053) Copyright © 2007 American Academy of Ophthalmology Terms and Conditions