Comparison of Low Versus High (>40 mm Hg) Pulse Pressure to Predict the Benefit of Cardiac Resynchronization Therapy for Heart Failure (from the Multicenter.

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Comparison of Low Versus High (>40 mm Hg) Pulse Pressure to Predict the Benefit of Cardiac Resynchronization Therapy for Heart Failure (from the Multicenter Automatic Defibrillator Implantation Trial-Cardiac Resynchronization Therapy Trial) Saadia Sherazi, MD, MS, Ilan Goldenberg, MD, Arthur J. Moss, MD, Scott Solomon, MD, Valentina Kutyifa, MD, PhD, Scott McNitt, MS, Abrar H. Shah, MD, David T. Huang, MD, Mehmet K. Aktas, MD, Wojciech Zareba, MD, PhD, Alon Barsheshet, MD American Journal of Cardiology Volume 114, Issue 7, Pages 1053-1058 (October 2014) DOI: 10.1016/j.amjcard.2014.07.014 Copyright © 2014 Elsevier Inc. Terms and Conditions

Figure 1 Distribution of baseline PP in CRT-D and LBBB patients. American Journal of Cardiology 2014 114, 1053-1058DOI: (10.1016/j.amjcard.2014.07.014) Copyright © 2014 Elsevier Inc. Terms and Conditions

Figure 2 Effects of CRT-D on echocardiographic measures in patients with high and low PP. ΔVolume/baseline = (1 year volume − baseline volume)/baseline volume. ΔSD/baseline = (1 year SD − baseline SD)/baseline SD. LVESV = left ventricular end-systolic volume; LVEDV = left ventricle end-diastolic; SD = standard deviation of dyssynchrony measure. The bars represent median values; p <0.05 for all 3 comparisons. American Journal of Cardiology 2014 114, 1053-1058DOI: (10.1016/j.amjcard.2014.07.014) Copyright © 2014 Elsevier Inc. Terms and Conditions

Figure 3 Kaplan-Meier estimates of probability of HF or death events after 1 year of follow-up in 2 groups of PP (lowest quartile [Q1] vs high quartiles [Q2–4]). American Journal of Cardiology 2014 114, 1053-1058DOI: (10.1016/j.amjcard.2014.07.014) Copyright © 2014 Elsevier Inc. Terms and Conditions