Precision Medicine: The Potential for Identifying Personalized Therapies for Patients with Gastro-Esophageal Cancer

Disclosures

Epidemiology

Risk factors

Gastric Cancer: Histology

TN Staging of Gastric Cancer

Stage and Outcomes

Therapy

First Line Metastatic Disease

First Line: HER2+ Disease

Second Line Metastatic Disease

A Heterogeneous Disease

Four Genomic Subtypes

PD-1 Inhibitors

Molecular Profiling – An Example

Molecular Profiling – An Example

Molecular Profiling – An Example

Molecular Profiling – An Example

Perthera and the Pancreatic Cancer Action Network partner on Know Your Tumor

Know Your Tumor Results to Date: Enrollment

Tissue Availability Data

Actionability: Specific Results

Actionable Findings in Gastric Cancer?

Pitfalls and Concerns

Is Molecular Profiling Cost Effective?

Thank You