Therapeutics 3: Antibiotics Tutoring By Alaina Darby

Anaerobes, Atypicals, and Fungus Swanson’s Section

Tips: Pay attention to objectives!! Know the diagram… rewrite it over and over a

JR was bitten by a rogue toddler JR was bitten by a rogue toddler. Which of the following is the least likely anaerobic pathogen? Lactobacillus Actinomyces Bacteroides Fusobacterium c

JB was bitten by a dog. His hand is inflamed and the pus was cultured JB was bitten by a dog. His hand is inflamed and the pus was cultured. However, the cultures come back negative. What does this mean? He probably has a fungal infection He probably has an anaerobic infection He probably is infected with a virus He has no infection. It must be something else. b

JR just finished a regimen of clindamycin. He has developed diarrhea JR just finished a regimen of clindamycin. He has developed diarrhea. Which of the following pathogens is the most likely cause? C. perfringens C. tetani C. difficile B. fragilis c

JR just finished a regimen of clindamycin. He has developed diarrhea JR just finished a regimen of clindamycin. He has developed diarrhea. His WBC count is 16,000 and sCr is 1.2 (baseline 1). Which of the following therapies is most appropriate? Metronidazole 500 mg PO Q8H for 14 days Metronidazole 500 mg IV Q8H for 14 days Vancomycin 125 mg PO Q6H for 14 days Vancomycin 125 mg IV Q6H for 14 days c

JR just finished a regimen of clindamycin. He has developed diarrhea JR just finished a regimen of clindamycin. He has developed diarrhea. His WBC count is 16,000 and sCr is 1.2 (baseline 1). Which of the following therapies is most appropriate if this is his second episode? Metronidazole 500 mg PO Q8H for 14 days Metronidazole 500 mg IV Q8H for 14 days Vancomycin 125 mg PO Q6H for 14 days Vancomycin 125 mg IV Q6H for 14 days c

JR just finished a regimen of clindamycin. He has developed diarrhea JR just finished a regimen of clindamycin. He has developed diarrhea. His WBC count is 16,000 and sCr is 1.2 (baseline 1). Which of the following therapies is most appropriate if this is his third episode? Metronidazole 500 mg PO Q8H for 14 days Metronidazole 500 mg IV Q8H for 14 days Vancomycin 125 mg PO Q6H for 14 days Vancomycin 125 mg IV Q6H for 14 days c

Which of the following would not be an appropriate option for treating an anaerobic infection? Augmentin Imipenem Clindamycin Ceftazidime d

Which of the following would not be an appropriate option for treating a b. frag infection? Augmentin Imipenem Clindamycin Metronidazole c

Which of the following would you choose to treat a b. frag infection? Gentamicin Moxifloxacin Bactrim Azithromycin b

BD has pneumonia. Which of the following symptoms would indicate that it might be an atypical organism? Cough Sputum production Tachycardia Abdominal pain d

BD has pneumonia. It presents with abdominal pain, bradycardia, and myalgias. What is the most likely pathogen? Chlamydia Mycobacterium Ureaplasma Rickettsia a

BD has pneumonia. It presents with abdominal pain, bradycardia, and myalgias. What would be first line treatment? Azithromycin Levofloxacin Docycycline Augmentin a

This is an atypical sight… A “Flock” of “Mice” who are “cycling” Macrolides: “mycins” Tetracyclines: “cyclines” Fluroquinolones: “floxacins” a

What is the doc for Rocky mountain spotted fever? Azithromycin 7-14 days Azithromycin x 1 dose Doxycycline 7-14 days Doxycycline x 1 dose c

Which of the following is most resistant to fluconazole? C. albicans C. lusitaniae C. glabrata C. krusei d

Which of the following exhibits the most resistance to a wide variety of agents? C. albicans C. lusitaniae C. glabrata C. krusei c

Which of the following is most sensitive to treatment? C. albicans C. lusitaniae C. glabrata C. krusei a

Which of the following cannot be treated with amphotericin b? C. albicans C. lusitaniae C. glabrata C. krusei b

Which of the following causes sinusitis, pneumonia, and CNS infections? Candida Cryptococcus Aspergillus Blastomycoses c

JD has an aspergillus infection. How should he be treated? Caspofungin Amphoteracin B Fluconazole Voriconazole d

For which of the following Candida infections is amphotericin B + Flucytosine the DOC? Blood stream infection UTI Meningitis Disseminated disease c