Pharmacokinetics of fentanyl after single intravenous injection and constant rate infusion in dogs Tadashi Sano, DVM, PhD, Ryohei Nishimura, DVM, PhD,

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Pharmacokinetics of fentanyl after single intravenous injection and constant rate infusion in dogs Tadashi Sano, DVM, PhD, Ryohei Nishimura, DVM, PhD, Hideko Kanazawa, PD, Eri Igarashi, PD, Yoshiko Nagata, PD, Manabu Mochizuki, DVM, PhD, Nobuo Sasaki, DVM, PhD Veterinary Anaesthesia and Analgesia Volume 33, Issue 4, Pages 266-273 (July 2006) DOI: 10.1111/j.1467-2995.2005.00266.x Copyright © 2006 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia Terms and Conditions

Figure 1 Plasma fentanyl concentration changes after rapid IV injection of 10 μg kg−1 in conscious dogs. Veterinary Anaesthesia and Analgesia 2006 33, 266-273DOI: (10.1111/j.1467-2995.2005.00266.x) Copyright © 2006 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia Terms and Conditions

Figure 2 Plasma fentanyl concentration changes in conscious dogs after rapid intravenous injection of 10 μg kg−1 followed by infusion (10 μg kg−1 hour−1) for 1 hour. Veterinary Anaesthesia and Analgesia 2006 33, 266-273DOI: (10.1111/j.1467-2995.2005.00266.x) Copyright © 2006 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia Terms and Conditions

Figure 3 Plasma fentanyl concentration changes in conscious dogs after rapid intravenous injection of 10 μg kg−1 followed by infusion (10 μg kg−1 hour−1) for 3 hours. Veterinary Anaesthesia and Analgesia 2006 33, 266-273DOI: (10.1111/j.1467-2995.2005.00266.x) Copyright © 2006 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia Terms and Conditions

Figure 4 Plasma fentanyl concentration changes in conscious dogs after rapid intravenous injection of 10 μg kg−1 followed by infusion (10 μg kg−1 hour−1) for 4 hours. Veterinary Anaesthesia and Analgesia 2006 33, 266-273DOI: (10.1111/j.1467-2995.2005.00266.x) Copyright © 2006 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia Terms and Conditions