Hepatitis Tutoring By Alaina Darby.

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Presentation transcript:

Hepatitis Tutoring By Alaina Darby

FK is a 65 yo nurse who just completed a mission trip to the Middle East. It is thought that she may have ingested contaminated water during her trip. What form of viral hepatitis should she be most concerned about acquiring? HIV HAV HBV HCV b

Immunoglobulin administration Increased hand washing FK is a 65 yo nurse who just completed a mission trip to the Middle East. It is thought that she may have ingested contaminated water during her trip. What should she do as prophylaxis against hepatitis after returning from her trip? Immunoglobulin administration Increased hand washing Antiviral administration Nothing a

FK is a 65 yo nurse who just completed a mission trip to the Middle East. It is thought that she may have ingested contaminated water during her trip. When would you expect to see symptoms should she develop hepatitis? Within 2 weeks Within 2 months Within 6 months Within 1 year b

Subsequent immunoglobulin administration Antiviral administration FK is a 65 yo nurse who just completed a mission trip to the Middle East. It is thought that she may have ingested contaminated water during her trip. Regardless of immunoglobulin prophylaxis, she develops a fever, dark urine, and itching along with RUQ pain. What should be done? Subsequent immunoglobulin administration Antiviral administration HAV vaccination Nothing d

FK is a 65 yo nurse who just completed a mission trip to the Middle East. It is thought that she may have ingested contaminated water during her trip. You prophylaxed with immunoglobulin and gave supportive care for viral hepatitis. It is now 4 months later, what vaccinations should you not give her at this time (assuming all are indicated)? MMR Shingles Pneumococcal Flu b

JS is a 25 yo nurse who was accidentally stuck by a needle JS is a 25 yo nurse who was accidentally stuck by a needle. Which of the following should she be most concerned about acquiring? HIV HAV HBV HCV c

JS is a 25 yo nurse who was accidentally stuck by a needle JS is a 25 yo nurse who was accidentally stuck by a needle. She is to receive prophylaxis for HBV. How long should she receive HBIG? 1 week 2 weeks 3 weeks 4 weeks a

JS is a 25 yo nurse who was accidentally stuck by a needle 6 weeks ago JS is a 25 yo nurse who was accidentally stuck by a needle 6 weeks ago. She has developed N/V, fever, and scleral icterus. Which of the following would be diagnostic of current HBV infection? HBV surface antigen Anti-HBs Anti-HBc HBV DNA 15,000 c

HBV… Blood Bodily fluids Baby (at birth) b

HBsAg(+), anti-HBc(+), IgM anti-HBc(+), anti-HBs(-) JS is a 25 yo nurse who was accidentally stuck by a needle 6 weeks ago. She has developed N/V, fever, and scleral icterus. Which of the following would you expect on serology? HBsAg(+), anti-HBc(+), IgM anti-HBc(+), anti-HBs(-) HBsAg(+), anti-HBc(+), IgM anti-HBc(+), anti-HBs(+) HBsAg(-), anti-HBc(+), IgM anti-HBc(+), anti-HBs(-) HBsAg(-), anti-HBc(+), IgM anti-HBc(+), anti-HBs(+) a

Serology… HBsAg… current infection Anti-HBc… is/was actually infected IgM ant-HBc… acute illness Anti-HBs… immune

JS is a 25 yo nurse who was accidentally stuck by a needle 6 weeks ago JS is a 25 yo nurse who was accidentally stuck by a needle 6 weeks ago. Which of the following would be indicative of liver inflammation but not necessarily liver function in this patient? INR AST/ALT Albumin Platelets b

JS is a 25 yo nurse who was accidentally stuck by a needle 6 weeks ago JS is a 25 yo nurse who was accidentally stuck by a needle 6 weeks ago. When should you start treating this patient for HBV hepatitis? HBV DNA 12,000, AST 90, ALT 140 HBV DNA 12,000, AST 160, ALT 90 HBV DNA 18,000, AST 90, ALT 100 HBV DNA 18,000, AST 160, ALT 100 a

Treat when… HBV DNA >20,000 Or ALT >2x ULN (>100)

Labs: HBV DNA 12,000, AST 90, ALT 140, SCr 1.6, K+ 4.9 JS is a 25 yo nurse who was accidentally stuck by a needle 6 weeks ago. Labs: HBV DNA 12,000, AST 90, ALT 140, SCr 1.6, K+ 4.9 Which of the following should be initiated? Adefovir Tenefovir Lamivudine Entecavir d

Labs: HBV DNA 12,000, AST 90, ALT 140, SCr 1.6, K+ 4.9 JS is a 25 yo nurse who was accidentally stuck by a needle 6 weeks ago. Labs: HBV DNA 12,000, AST 90, ALT 140, SCr 1.6, K+ 4.9 Which of the following might be preferred in this patient if she already had been diagnosed with HIV? Adefovir Tenefovir Lamivudine Entecavir c

Healthcare worker born in 1987 Dialysis patient born in 1963 Which of the following patients would not be indicated for the HBV vaccine? Healthcare worker born in 1987 Dialysis patient born in 1963 Person traveling to Australia born in 1950 Infant born 2 days ago (mother is negative) c

BK is a 62 yo WM who presents to you complaining of abdominal pain and dark urine. Which of the following tests may not be helpful at this time? ALT HAV/HBV testing Anti-HCV antibodies HCV RNA c

BK is a 62 yo WM who presents to you complaining of abdominal pain and dark urine. His testing comes back positive for HCV RNA and negative for Anti-HCV antibodies. What is your assessment? Chronic HCV HCV resolution Acute HCV No infection c

HCV RNA negative, Anti-HCV negative BK is a 62 yo WM who presents to you complaining of abdominal pain and dark urine. If he had previously been diagnosed with chronic HCV, what would you expect to see if this is an acute episode? HCV RNA negative, Anti-HCV negative HCV RNA negative, Anti-HCV positive HCV RNA positive, Anti-HCV negative HCV RNA positive, Anti-HCV positive d

HCV RNA negative, Anti-HCV negative BK is a 62 yo WM who presents to you complaining of abdominal pain and dark urine. What would you expect to see if treatment is successful and HCV resolves? HCV RNA negative, Anti-HCV negative HCV RNA negative, Anti-HCV positive HCV RNA positive, Anti-HCV negative HCV RNA positive, Anti-HCV positive b

HCV RNA negative x 4 weeks Anti-HCV negative x 4 weeks BK is a 62 yo WM who presents to you complaining of abdominal pain and dark urine. How would you determine if treatment is successful and HCV resolves? HCV RNA negative x 4 weeks Anti-HCV negative x 4 weeks HCV RNA negative x 12 weeks Anti-HCV negative x 12 weeks c

BK is a 62 yo WM who presents to you complaining of abdominal pain and dark urine. After treatment, HCV RNA is negative x 16 weeks. What is this considered? SVR RVR EVR ETR a