Toronto region is the only growing metro region in north America The region welcomes about 100,000 new residents every year. Canada’s skills-based immigration system ensures many are highly skilled 53% 13% 22% 27% 29% Source: Statistics Canada (Toronto & Montreal Census Metropolitan Areas) and US Census (US Metropolitan Statistical Areas). 1990 for US Cities, 1991 for Canadian Cities

Toronto region: A global Cluster Toronto region has a solid foundation for dynamic growth. We have the scale and scope to place among the world’s top human health science clusters. Source: Jones, Lang, LaSalle. Life Sciences Cluster Report 2014 Briefing Document 150620

Toronto Region human health + sciences cluster North Downtown “High Tech Capital” 100 ICT companies 1 university, 3 colleges Multinational generic, digital and medical device companies Neutraceutical and manufacturing operations “Discovery district” 9 research hospitals, 10 community hospitals 3 universities, 3 colleges, 37 research institutes 160 biotechnology and medical device companies east West “Advanced manufacturing” Multinational generics and digital companies Laboratories, manufacturing and warehousing operations 1 university campus, 3 hospitals “Pill Hill” 30 multinational pharma and medical device companies 30+ small and medium biotechnology and medical device companies Laboratories, manufacturing and warehousing operations 1 university campus, 1 college, 6 hospitals Briefing Document 150620

Global clinical trials World-leading Academic & Translational research Perfect mix of science, business and lifestyle in the only growing metro region A centre for Global clinical trials World-leading Academic & Translational research Briefing Document 150620

Toronto Region areas of expertise/Assets THERAPEUTIC AREA EXPERTISE CANCER NEUROSCIENCE CHRONIC DISEASES Cellular and Regenerative Medicine Genomics Imaging and Medical Devices Digital and Informatics TECHNOLOGY VEHICLE EXPERTISE

Advanced business environment Lower Cost of doing business Source: Competitive Alternatives, KPMG’s Guide to International Business Location Costs - 2014 Edition Canada has a cost advantage compared to U.S. The 3 major U.S. health sciences clusters are above the U.S. baseline for costs of doing business (Boston, NY, SF) Source: KPMG. Competitive Alternatives: 2014 Edition. Pp. 20-22