TO IMPROVE THE AVAILIBILITY OF ACT

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Presentation transcript:

TO IMPROVE THE AVAILIBILITY OF ACT THE ARTEPAL PROJECT TO IMPROVE THE AVAILIBILITY OF ACT Nairobi03/2006

ARTEPAL 1/ THE PROJECT PROJECT OF AEDES FOUNDATION Agreed and financed by E.U. on 3 years 3 sections: technology transfer, pregnant women, distribution Oteci (senior-experts) in charge of technology transfer under control of a technical and scientific committee. OBJECTIVE: IMPROVE AVAILIBILTY OF ACTs Nairobi03/2006

ARTEPAL 2/SITUATION Evaluation of projects in all the supply chain (plantations, extraction, pharma) and in different regions Evaluation of extraction processes Establishing connections between different partners Support in GMPs at different levels in connection with WHO/pre-qualification. Nairobi03/2006

ARTEPAL 3/ FINDINGS Numerous projects restarting basic studies available in the literature Numerous plantation projects without available extraction unit. Numerous projects without knowledge of the commercial possibilities and quality requirements Numerous questions asked to WHO/RBM/MMSS and others Nairobi03/2006

ARTEPAL 3/FINDINGS Since the meeting in Arusha, risks of inadaptation of demand and supply are increasing. Quantities Quality Recommandation of WHO for only ACTs may deeply change the demand Nairobi03/2006

ARTEPAL 4/PROPOSAL S WHO/RBM/MMSS with MSH/RPM Plus intend to produce a guide to API production covering : Cultivation issues on artemisia annua: Seeds: sourcing, quantities needed Planting, growing conditions, climate… Areas of cultivation and surfaces Major issues, agricultural and financial Average biomass and artemisini content Nairobi03/2006

ARTEPAL 4/PROPOSALS Production of Artemisinin Extraction units: Where Capacity, quantity and time of production Kind pf process Possibilities to extract other products Constraints: technical, financial Issues involved with respect to the quality of finished ACTs: GAP GMP DMF… Nairobi03/2006

ARTEPAL 4/PROPOSALS Main deliverable: « Market analysis »of the current situation in terms of capacity, quality issues,.. A guide for resources, contacts Table or tool to estimate cultivation and extraction needs across the production chain. Nairobi03/2006