Martina Mosing, Paul MacFarlane, David Bardell, Laura Lüthi, Peter J

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Continuous positive airway pressure (CPAP) decreases pulmonary shunt in anaesthetized horses Martina Mosing, Paul MacFarlane, David Bardell, Laura Lüthi, Peter J. Cripps, Regula Bettschart‐Wolfensberger Veterinary Anaesthesia and Analgesia Volume 43, Issue 6, Pages 611-622 (November 2016) DOI: 10.1111/vaa.12357 Copyright © 2016 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia Terms and Conditions

Figure 1 Flow diagram illustrating the number of horses included in the statistical analysis at each measurement time‐point (M). CPAP, continuous positive airway pressure. Veterinary Anaesthesia and Analgesia 2016 43, 611-622DOI: (10.1111/vaa.12357) Copyright © 2016 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia Terms and Conditions

Figure 2 Time curves for (a) arterial oxygen partial pressure (PaO2) (p < 0.001) and (b) shunt ratio (p < 0.001) in horses receiving and not receiving continuous positive airway pressure (CPAP) during 360 minutes of anaesthesia. Time had a significant influence on both variables in both groups. Data are expressed as the mean ± standard deviation. Veterinary Anaesthesia and Analgesia 2016 43, 611-622DOI: (10.1111/vaa.12357) Copyright © 2016 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia Terms and Conditions

Figure 3 Time curves for (a) cardiac output (p = 0.221), (b) oxygen delivery ( D ˙ O 2 ) (p = 0.305), (c) haemoglobin levels (p < 0.001), and (d) arterial oxygen content (CaO2) (p = 0.186) in horses receiving and not receiving continuous positive airway pressure (CPAP) during 360 minutes of anaesthesia. Time had a significant influence on cardiac output and oxygen delivery in both groups. Data are expressed as the mean ± standard deviation. Veterinary Anaesthesia and Analgesia 2016 43, 611-622DOI: (10.1111/vaa.12357) Copyright © 2016 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia Terms and Conditions

Figure 4 Time curves for (a) arterial carbon dioxide partial pressure (PaCO2) (p = 0.96), and (b) central venous pressure (CVP) (p < 0.001) in horses receiving and not receiving continuous positive airway pressure (CPAP) during 360 minutes of anaesthesia. Time had a significant influence on both variables in both groups. Data are expressed as the mean ± standard deviation. Veterinary Anaesthesia and Analgesia 2016 43, 611-622DOI: (10.1111/vaa.12357) Copyright © 2016 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia Terms and Conditions