Transplant Overview By Alaina Darby

Coronary artery disease Short gut syndrome Transplant for which of the following disease states would have the best graft survival? Coronary artery disease Short gut syndrome Hypertension nephrosclerosis Non-choleostatic cirrhosis c

Coronary artery disease Short gut syndrome Transplant for which of the following disease states would have the best patient survival? Coronary artery disease Short gut syndrome Hypertension nephrosclerosis Non-choleostatic cirrhosis c

Coronary artery disease Short gut syndrome Transplant for which of the following disease states would need the most immunosuppression? Coronary artery disease Short gut syndrome Hypertension nephrosclerosis Non-choleostatic cirrhosis b

Coronary artery disease Short gut syndrome Transplant for which of the following disease states would be determined by the MELD score for allocation of the organ? Coronary artery disease Short gut syndrome Hypertension nephrosclerosis Non-choleostatic cirrhosis d

22 yo alcoholic who has been clean for 6 months, MELD score 40 Which of the following patients would be most likely to receive a liver transplant? 22 yo alcoholic who has been clean for 6 months, MELD score 40 28 yo alcoholic who has been clean for 6 months, MELD score 36 22 yo alcoholic who has been clean for 1 year, MELD score 28 28 yo alcoholic who has been clean for 1 year, MELD score 44 d

Which of the following is not an indication for lung transplant? Emphysema Pulmonary embolism COPD Cystic fibrosis b

Hypoglycemic unawareness Which of the following would not be a likely indication for pancreas transplant? T1DM Early stage T2DM Late stage T2DM Hypoglycemic unawareness b

Which of the following signals is described by the following? Costimulatory binding of antigen presenting cell with T cell Signal 1 Signal 2 Signal 3 b

Which of the following signals is described by the following? Presentation of foreign antigen to T cell Signal 1 Signal 2 Signal 3 a

Which of the following signals is described by the following? Involves the major histocompatibility complex (MHC) Signal 1 Signal 2 Signal 3 a

Which of the following signals is described by the following? Binding of IL2 to the receptor Signal 1 Signal 2 Signal 3 c

Which of the following signals is described by the following? Results in the production of calcineurin Signal 1 Signal 2 Signal 3 a and b

Which of the following signals is described by the following? Upregulates mTOR Signal 1 Signal 2 Signal 3 c

Which of the following is not a member of innate immunity? Phagocytes Plasma cells Complement system Natural killer cells b

Which of the following does not act as an antigen presenting cell? T-helper cells Dendritic cells Macrophages B-lymphocytes a

Which of the following phagocytes is most involved in acute cellular rejection? Neutrophils Macrophages Eosinophils b

Your patient is C4d positive. What does this tell you? Rejection is antibody mediated Rejection is T cell mediated Rejection is NK cell mediated Rejection is complement mediated a

Which of the following produces cytokines? Plasma cells Memory cells T helper cells T killer cells c

Which of the following produces antibodies? Plasma cells Memory cells T helper cells T killer cells a

Which of the following has the longest half life? Plasma cells Memory cells T helper cells T killer cells b

Which of the following responds to HLA-DR? Plasma cells Memory cells T helper cells T killer cells c

Which of the following responds to HLA-B? Plasma cells Memory cells T helper cells T killer cells d

Which of the following are also known as CD8 cells? Plasma cells Memory cells T helper cells T killer cells d

Which of the following responds to antigens on APCs only? Plasma cells Memory cells T helper cells T killer cells c

Which of the following responds to proteins on all nucleated cells? Plasma cells Memory cells T helper cells T killer cells d

Chronic T-cell mediated Acute antibody mediated RT received a kidney transplant 2 months ago and is now experiencing tubular atrophy in that kidney. How would the rejection be classified? Acute T-cell mediated Chronic T-cell mediated Acute antibody mediated Chronic antibody mediated c

Lymphocyte depleting agents Rituximab RT received a kidney transplant 2 months ago and is now experiencing tubular atrophy in that kidney. What is the least preferred option for treatment? IVID Steroids Lymphocyte depleting agents Rituximab c

How many HLA matches are recorded above? 1 2 3 4 DR Donor 6 8 24 72 23 Recipient 4 6 55 68 23 87 c

How many HLA matches are recorded above? 1 2 3 4 DR Donor 6 8 24 72 21 23 Recipient 6 6 55 68 23 87 b

JT is a 22 yo AAF who had a pancreatic transplant 2 months ago JT is a 22 yo AAF who had a pancreatic transplant 2 months ago. After the pancreas transplant she had to receive insulin for a short time. The donor pancreas was a HLA match of 5 and PRA of 50%. How many high risk factors does she have? 2 3 4 5 d AA, pancreas, delayed function, PRA, deceased donor

JT is a 22 yo AAF who had a pancreatic transplant 2 months ago JT is a 22 yo AAF who had a pancreatic transplant 2 months ago. After the pancreas transplant she had to receive insulin for a short time. The donor pancreas was a HLA match of 5 and PRA of 50%. How many low risk factors does she have? 2 3 4 5 a Primary, HLA

Anti-T cell + CI + S + mTOR JT is a 22 yo AAF who had a pancreatic transplant 2 months ago. After the pancreas transplant she had to receive insulin for a short time. The donor pancreas was a HLA match of 5 and PRA of 50%. What treatment should she receive? AM + CI CI + AM + mTOR CI + S + mTOR Anti-T cell + CI + S + mTOR a

Anti-T cell + CI + S + mTOR JT is a 22 yo AAF who had a pancreatic transplant 2 months ago. After the pancreas transplant she had to receive insulin for a short time. The donor pancreas was a HLA match of 5 and PRA of 50%. What treatment should she receive if she were white? AM + CI CI + AM + mTOR CI + S + mTOR Anti-T cell + CI + S + mTOR a

Anti-T cell + CI + S + mTOR JT is a 22 yo AAF who had a pancreatic transplant 2 months ago. After the pancreas transplant she had to receive insulin for a short time. The donor pancreas was a HLA match of 5 and PRA of 50%. What treatment should she receive if she were 16? AM + CI CI + AM + mTOR CI + S + mTOR Anti-T cell + CI + S + mTOR c