Elements of the Immune System and their Roles in Defense

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Presentation transcript:

Elements of the Immune System and their Roles in Defense Peter Parham The Immune System Fourth Edition Chapter 1 Elements of the Immune System and their Roles in Defense Copyright © Garland Science 2015

CHAPTER CONTENTS 1-1 Numerous commensal microorganisms inhabit healthy human bodies 1-2 Pathogens are infectious organisms that cause disease 1-3 The skin and mucosal surfaces form barriers against infection 1-4 The innate immune response causes inflammation at sites of infection 1-5 The adaptive immune response adds to an ongoing innate immune response 1-6 Adaptive immunity is better understood than innate immunity 1-7 Immune system cells with different functions all derive from hematopoietic stem cells

CHAPTER CONTENTS 1-8 Immunoglobulins and T-cell receptors are the diverse lymphocyte receptors of adaptive immunity 1-9 On encountering their specific antigen, B cells and T cells differentiate into effector cells 1-10 Antibodies bind to pathogens and cause their inactivation or destruction 1-11 Most lymphocytes are present in specialized lymphoid tissues 1-12 Adaptive immunity is initiated in secondary lymphoid tissues 1-13 The spleen provides adaptive immunity to blood infections 1-14 Most secondary lymphoid tissue is associated with the gut

Introduction

Introduction

Introduction

ELEMENTS OF THE IMMUNE SYSTEM AND THEIR ROLES IN DEFENSE 1-1 Numerous commensal microorganisms inhabit healthy human bodies

1-1 Numerous commensal microorganisms inhabit healthy human bodies

ELEMENTS OF THE IMMUNE SYSTEM AND THEIR ROLES IN DEFENSE 1-2 Pathogens are infectious organisms that cause disease

1-2 Pathogens are infectious organisms that cause disease

1-2 Pathogens are infectious organisms that cause disease

1-2 Pathogens are infectious organisms that cause disease

1-2 Pathogens are infectious organisms that cause disease

1-2 Pathogens are infectious organisms that cause disease

1-2 Pathogens are infectious organisms that cause disease

ELEMENTS OF THE IMMUNE SYSTEM AND THEIR ROLES IN DEFENSE 1-3 The skin and mucosal surfaces form barriers against infection

1-3 The skin and mucosal surfaces form barriers against infection

ELEMENTS OF THE IMMUNE SYSTEM AND THEIR ROLES IN DEFENSE 1-4 The innate immune response causes inflammation at sites of infection

1-4 The innate immune response causes inflammation at sites of infection

1-4 The innate immune response causes inflammation at sites of infection

ELEMENTS OF THE IMMUNE SYSTEM AND THEIR ROLES IN DEFENSE 1-5 The adaptive immune response adds to an ongoing innate immune response

1-5 The adaptive immune response adds to an ongoing innate immune response

1-5 The adaptive immune response adds to an ongoing innate immune response

ELEMENTS OF THE IMMUNE SYSTEM AND THEIR ROLES IN DEFENSE 1-6 Adaptive immunity is better understood than innate immunity

1-6 Adaptive immunity is better understood than innate immunity

ELEMENTS OF THE IMMUNE SYSTEM AND THEIR ROLES IN DEFENSE 1-7 Immune system cells with different functions all derive from hematopoietic stem cells

1-7 Immune system cells with different functions all derive from hematopoietic stem cells

1-7 Immune system cells with different functions all derive from hematopoietic stem cells

1-7 Immune system cells with different functions all derive from hematopoietic stem cells

1-7 Immune system cells with different functions all derive from hematopoietic stem cells

1-7 Immune system cells with different functions all derive from hematopoietic stem cells

1-7 Immune system cells with different functions all derive from hematopoietic stem cells

1-7 Immune system cells with different functions all derive from hematopoietic stem cells

1-7 Immune system cells with different functions all derive from hematopoietic stem cells

1-7 Immune system cells with different functions all derive from hematopoietic stem cells

ELEMENTS OF THE IMMUNE SYSTEM AND THEIR ROLES IN DEFENSE 1-8 Immunoglobulins and T-cell receptors are the diverse lymphocyte receptors of adaptive immunity

1-8 Immunoglobulins and T-cell receptors are the diverse lymphocyte receptors of adaptive immunity

ELEMENTS OF THE IMMUNE SYSTEM AND THEIR ROLES IN DEFENSE 1-9 On encountering their specific antigen, B cells and T cells differentiate into effector cells

ELEMENTS OF THE IMMUNE SYSTEM AND THEIR ROLES IN DEFENSE 1-10 Antibodies bind to pathogens and cause their inactivation or destruction

1-10 Antibodies bind to pathogens and cause their inactivation or destruction

ELEMENTS OF THE IMMUNE SYSTEM AND THEIR ROLES IN DEFENSE 1-11 Most lymphocytes are present in specialized lymphoid tissues

1-11 Most lymphocytes are present in specialized lymphoid tissues

1-11 Most lymphocytes are present in specialized lymphoid tissues

ELEMENTS OF THE IMMUNE SYSTEM AND THEIR ROLES IN DEFENSE 1-12 Adaptive immunity is initiated in secondary lymphoid tissues

1-12 Adaptive immunity is initiated in secondary lymphoid tissues

1-12 Adaptive immunity is initiated in secondary lymphoid tissues

1-12 Adaptive immunity is initiated in secondary lymphoid tissues

1-12 Adaptive immunity is initiated in secondary lymphoid tissues

1-12 Adaptive immunity is initiated in secondary lymphoid tissues

ELEMENTS OF THE IMMUNE SYSTEM AND THEIR ROLES IN DEFENSE 1-13 The spleen provides adaptive immunity to blood infections

1-13 The spleen provides adaptive immunity to blood infections

1-13 The spleen provides adaptive immunity to blood infections

1-13 The spleen provides adaptive immunity to blood infections

1-13 The spleen provides adaptive immunity to blood infections

ELEMENTS OF THE IMMUNE SYSTEM AND THEIR ROLES IN DEFENSE 1-14 Most secondary lymphoid tissue is associated with the gut

1-14 Most secondary lymphoid tissue is associated with the gut