Negative impact of borderline global cognitive scores on quality of life after subthalamic nucleus stimulation in Parkinson's disease  Karsten Witt, Christine Daniels, Paul Krack, Jens Volkmann, Markus O. Pinsker, Manja Kloss, Volker Tronnier, Alfons Schnitzler, Lars Wojtecki, Kai Bötzel, Adrian Danek, Rüdiger Hilker, Volker Sturm, Andreas Kupsch, Elfriede Karner, Günther Deuschl  Journal of the Neurological Sciences  Volume 310, Issue 1, Pages 261-266 (November 2011) DOI: 10.1016/j.jns.2011.06.028 Copyright © 2011 Elsevier B.V. Terms and Conditions

Fig. 1 Changes in the PDQ-39 scores between baseline and 6months are shown for patients of the STN–DBS group (blue) and patients of the BMT group (green). Changes in the positive direction indicate an improvement in QoL, mean and SEM are shown. Patients were split into 4 groups according their performance on the MDRS at baseline (130–137, 138–140, 141–142 and 143–144 points). Patients scoring in the lowest quartile of the MDRS at baseline did not improve in QoL after STN–DBS compared to patients within the lowest quartile of the MDRS in the BMT group. ** indicates significant differences on a p value<0.01. Journal of the Neurological Sciences 2011 310, 261-266DOI: (10.1016/j.jns.2011.06.028) Copyright © 2011 Elsevier B.V. Terms and Conditions

Fig. 2 Changes in the PDQ-39 subscores between patients scored in the lowest quartile of the MDRS. The BMT group is displayed in green, the STN–DBS group in blue. Patients in the 1st to 3rd quartile of the STN–DBS group significantly improve in “mobility,” “activities in daily living,” “emotional well-being” and “stigma” (*p<0.05). Journal of the Neurological Sciences 2011 310, 261-266DOI: (10.1016/j.jns.2011.06.028) Copyright © 2011 Elsevier B.V. Terms and Conditions