David Malek, VP Business Development BD Presentation David Malek, VP Business Development BioLineRx davidm@biolinerx.com 054-5300366

Forward Looking Statements This presentation contains "forward-looking statements." These statements include words like "may," "expects," "believes," “plans,” “scheduled," and "intends," and describe opinions about future events. These forward-looking statements involve known and unknown risks and uncertainties that may cause the actual results, performance or achievements of BioLineRx to be materially different from any future results, performance or achievements expressed or implied by such forward-looking statements.

BioLineRx - General Founded in 2003 by Teva and other key players in Israeli Life Sciences industry Bridge “development gap” for Israeli assets Leverage carefully selected early-stage technology, primarily at academia level, following proof of concept in animals (at a minimum) Invest 3-6 years in asset through to major catalyst Partner the asset (depending on the stage) Current pipeline of 10 assets, 6 in clinical development ~55 employees, of which ~40 with advanced degrees

Efficient Project Development Infrastructure Expert Project Managers Medical and Clinical Team BD In-licensing and Out-licensing Multiple Projects Pre-Clinical Team Our expert teams work in synergy to advance the projects as quickly and efficiently as possible Chemistry Team (Organic, Analytical, Bioanalytical, Formulation) Intellectual Property Experts Regulatory Affairs Team

What is BD in biopharma companies? Example via biolinerx

In BioLineRx, BD Has 3 Major Responsibilities Scouting & in-licensing Search for innovative and attractive projects, in Israel and abroad Evaluate projects: science, development, clinical need, commercial opportunity, IP Negotiate with inventors and manage the alliance Out-licensing The way in which most companies make revenues Identify partners, contact them, present and persuade, manage relationship Negotiate and manage the alliance “Commercial Sense” Identify best value for the project from the commercial perspective Collaborate with R&D to find overlap between commercial potential, scientific fit and development feasibility Continuously monitor and analyze the impact of changes in the market/data

The Team Structure Supports These Roles Scout Gideon Stein Scout Portfolio Manager Lior Teitelbaum Scientific Evaluation Leader Victoria Balannik Out Licensing Tomer Bahar Analyst Inbal Michaelovici

Career paths to bd roles

What is the Background of the Team Members? Education: MD, MBA Experience: physician, entrepreneur Gideon Stein Education: MSc., MBA Experience: VC analyst, small medical device company Lior Teitelbaum Education: PhD Experience: Post-doc, researcher, Amazon Victoria Balannik Education: MSc., MBA Experience: PwC, Hadasit Tomer Bahar Education: PhD Experience: Researcher Inbal Michaelovici

What Are the Key Career Paths? Direct to industry Typically junior Better chance at companies with larger BD teams, TTOs Investment community Relatively few positions, more in the lines of temporary experience Typically analyst positions R&D first Work for several years in R&D roles and try to “progress” to BD Typically easier within the same company Can also work for entrepreneurs Service Industry “satellite” companies supporting the industry: IP law firms, accounting firms, etc.

תכל'ס, מה לעשות? Read business news and literature all the time Free sources are fine: FierceBiotech, FirstWord, etc. Gain as wide a base as possible in your academic experience In BD, over-specialization is typically NOT a good thing Show you’re a fast-learner (which you’ll need to be in order to switch to business) Get some part-time experience/project Create some level of confidence and differentiation You will learn a lot about the fit Network (with the relevant people) Strong labs/recommendations help MBA: only if you really want to Don’t be afraid to take tasks that you have no experience/qualifications for