Image 1 Melanocytes in control anorectal mucosa (hemorrhoids) highlighted by MITF ( A ) and HMB45 ( B ) immunostains as single, scattered, and basally located intraepithelial cells (×200). From: Assessment of Melanocyte Density in Anorectal Mucosa for the Evaluation of Surgical Margins in Primary Anorectal Melanoma Am J Clin Pathol. 2016;145(5):626-634. doi:10.1093/ajcp/aqw047 Am J Clin Pathol | © American Society for Clinical Pathology, 2016. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com 1