P-WT-325- Corneal Topography In Childhood Glaucoma Patients

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P-WT-325- Corneal Topography In Childhood Glaucoma Patients Perucho-González L, Sáenz-Francés F, Morales-Fernández L, Martínez de la Casa JM, Méndez-Hernández C, García-Feijoó J Hospital Clínico San Carlos, Madrid, Spain PURPOSE To investigated the topography and the irregular astigmatism of the cornea in eyes with childhood glaucoma (CG). METHODS Cross-sectional study in which 94 eyes of 55 CG patients and 66 eyes of 34 age-matched controls underwent measurements using Pentacam. Corneal topographic changes and 4th order aberrations were evaluated on Pentacam in eyes with CG and those changes were compared with the control eyes. RESULTS Variable CG eyes (n94) Control eyes (n66) p value* Age (years) 5.642.85 5.203.25 0.376 Anterior Max. Elevation (AME) 9.008.79 3.252.26 < 0.001 Posterior Apex Elevation (PAE) 3.1911.89 0.902.95 0.039 Posterior Max. Elevation (PME) 30.8328.21 7.588.59 Anterior Apex Elevation (AAE) 2.883.73 2.444.65 0.300 Anterior Central Elevation (ACE) 2.421.98 2.492.05 0.127 Posterior Central Elevation (PCE) 2.8115.05 1.073.15 0.057 Anterior Chamber Volume (ACV) 267.1964.82 194.2034.98 < 0.001 Anterior Chamber Depth (ACD) 3.690.64 3.140.29 Corneal astigmatism (Pmax, diopter cylinder) 40.79 3.01 44.091.74 < 0.001 However, 4th order aberrations measured by coma were statistically significantly higher in CG group compared to the values in healthy patients (Mann- Whitney test, z= -4.69, p<0.001). CONCLUSION We found that CG causes a significant increase in posterior maximun and apex corneal elevation; anterior maximun corneal elevation; and in anterior chamber size (both volume and depth). We also found more rate of irregular astigmatism in CG patients compared to controls. REFERENCES Patil B, Tandon R & Sharma N (2015): Corneal changes in childhood glaucoma. Ophthalmology 122: 87–92.