Copyright © 2010 American Medical Association. All rights reserved. From: Intranasal Midazolam vs Rectal Diazepam for the Home Treatment of Acute Seizures in Pediatric Patients With Epilepsy Arch Pediatr Adolesc Med. 2010;164(8):747-753. doi:10.1001/archpediatrics.2010.130 Figure Legend: Patient enrollment flowchart. IN-MMAD indicates Intranasal-Midazolam Mucosal Atomization Device; RD, rectal diazepam. Date of download: 10/10/2017 Copyright © 2010 American Medical Association. All rights reserved.

Copyright © 2010 American Medical Association. All rights reserved. From: Intranasal Midazolam vs Rectal Diazepam for the Home Treatment of Acute Seizures in Pediatric Patients With Epilepsy Arch Pediatr Adolesc Med. 2010;164(8):747-753. doi:10.1001/archpediatrics.2010.130 Figure Legend: Time from medication use to seizure cessation (difference, 1.3 minutes; 95% confidence interval, 0.0-3.5; P = .09). Confidence intervals and P values were calculated using Wilcoxon rank sum tests and Mann-Whitney U tests. IN-MMAD indicates Intranasal-Midazolam Mucosal Atomization Device; RD, rectal diazepam. Date of download: 10/10/2017 Copyright © 2010 American Medical Association. All rights reserved.

Copyright © 2010 American Medical Association. All rights reserved. From: Intranasal Midazolam vs Rectal Diazepam for the Home Treatment of Acute Seizures in Pediatric Patients With Epilepsy Arch Pediatr Adolesc Med. 2010;164(8):747-753. doi:10.1001/archpediatrics.2010.130 Figure Legend: Witnessed total seizure time (difference, 2.0 minutes; 95% confidence interval, 1.0-5.7; P = .25). Confidence intervals and P values were calculated using Wilcoxon rank sum tests and Mann-Whitney Utests. IN-MMAD indicates Intranasal-Midazolam Mucosal Atomization Device; RD, rectal diazepam. Date of download: 10/10/2017 Copyright © 2010 American Medical Association. All rights reserved.

Copyright © 2010 American Medical Association. All rights reserved. From: Intranasal Midazolam vs Rectal Diazepam for the Home Treatment of Acute Seizures in Pediatric Patients With Epilepsy Arch Pediatr Adolesc Med. 2010;164(8):747-753. doi:10.1001/archpediatrics.2010.130 Figure Legend: Witnessed time to medication administration (difference, 0.0 minutes; 95% confidence interval, −1.0 to 1.0; P = .57). Confidence intervals and P values were calculated using Wilcoxon rank sum tests and Mann-Whitney U tests. IN-MMAD indicates Intranasal-Midazolam Mucosal Atomization Device; RD, rectal diazepam. Date of download: 10/10/2017 Copyright © 2010 American Medical Association. All rights reserved.