GUT PHYSIOLOGY Motility-II Dr. Jack Grider Rm Sanger Hall

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GUT PHYSIOLOGY Motility-II Dr. Jack Grider Rm 12-004 Sanger Hall 828-1853 jgrider@vcu.edu 2009

Motility: Intestine Three types of normal motility patterns in intestine Peristalsis Segmentation

Motility: Intestine Two types of abnormal motility patterns in intestine

Motility: Intestine Two types of motility patterns predominate in the postprandial intestine: peristalsis (- - -) and segmentation (▼)

Motility: Intestinal Peristalsis

Motility: Intestinal Peristalsis Peristalsis is a 2-component short arc reflex

Motility: Intestinal Peristalsis Chemical & mechanical stimulation / /Tk/NPY (IPAN) Distension mucosa (Extrinsic Afferent) GABA/GRP GABA/GRP CGRP Primary afferent orad caudad

Motility: Intestinal Segmentation

Motility: Intestinal Segmentation

Motility: Intestinal Segmentation

Phase Phase II Phase III Phase I Motility: Intestine Interdigestive Motility Phase Phase II Phase III Phase I Myoelectrical Activity Contractile Activity

Motility: Intestine

Motility: Intestine The simple motility patterns governed by short arc reflexes and electrical activity are further modified by Long Arc Reflexes such as the Intestino-Intestinal reflex. There are many others.

Motility: Intestine

Motility:Colon

Motility: Colon Mass Movement Or Giant Contractions Mixing Movements Peristaltic & Antiperistaltic

Motility:Defecation Reflex

Motility: Defecation Extracolonic muscles play an important role in defecation

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