Dietary whey protein lowers serum C-peptide concentration and duodenal SREBP-1c mRNA abundance, and reduces occurrence of duodenal tumors and colon aberrant.

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Dietary whey protein lowers serum C-peptide concentration and duodenal SREBP-1c mRNA abundance, and reduces occurrence of duodenal tumors and colon aberrant crypt foci in azoxymethane-treated male rats  Rijin Xiao, Julie A. Carter, Amanda L. Linz, Matthew Ferguson, Thomas M. Badger, Frank A. Simmen  Journal of Nutritional Biochemistry  Volume 17, Issue 9, Pages 626-634 (September 2006) DOI: 10.1016/j.jnutbio.2005.11.008 Copyright © 2006 Elsevier Inc. Terms and Conditions

Fig. 4 SREBP-1c mRNA abundance in proximal small intestine (SI) (A, B) and midcolon (C) of nontumored animals at 6 weeks (A) and 23 weeks (B, C) post-AOM. Real-time reverse transcription PCR quantification of SREBP-1c mRNA was performed and the data normalized to cyclophilin mRNA. The mean value for the CAS-AOM group was set at 100%. P values indicate significant differences between the WPH-AOM and CAS-AOM groups as well as the CAS-vehicle-treated and CAS-AOM groups. Journal of Nutritional Biochemistry 2006 17, 626-634DOI: (10.1016/j.jnutbio.2005.11.008) Copyright © 2006 Elsevier Inc. Terms and Conditions