Genetic and environmental determinants of total and high-molecular weight adiponectin in families with low HDL-cholesterol and early onset coronary heart.

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Genetic and environmental determinants of total and high-molecular weight adiponectin in families with low HDL-cholesterol and early onset coronary heart disease Tiia Kangas-Kontio, Anne Huotari, Heli Ruotsalainen, Karl-Heinz Herzig, Minna Tamminen, Mika Ala-Korpela, Markku J. Savolainen, Sakari Kakko Atherosclerosis Volume 210, Issue 2, Pages 479-485 (June 2010) DOI: 10.1016/j.atherosclerosis.2009.12.022 Copyright © 2009 Elsevier Ireland Ltd Terms and Conditions

Fig. 1 Results of the genome-wide quantitative univariate (a) and bivariate (b) analysis. All genotyped markers were included in the analysis. The X-axis indicates the distance (cM) from the p-terminus of the chromosome and the Y-axis indicates the LOD score. The solid line indicates the results of the multipoint analysis and the filled diamonds the results of two-point analysis using only sex as a covariate. The dashed line represents the results of the multipoint analysis and the circles the results of two-point analysis using sex and BMI as covariates. Chr, chromosome; HMW, high-molecular weight; HDL-C, high-density lipoprotein cholesterol. Atherosclerosis 2010 210, 479-485DOI: (10.1016/j.atherosclerosis.2009.12.022) Copyright © 2009 Elsevier Ireland Ltd Terms and Conditions