Adapted from Montori et al,1 by permission of the publisher Adapted from Montori et al,1 by permission of the publisher. Copyright © 2005, Canadian Medical Association. Source: Spectrum Bias, Users' Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice, 3rd ed Citation: Guyatt G, Rennie D, Meade MO, Cook DJ. Users' Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice, 3rd ed; 2015 Available at: http://jamaevidence.mhmedical.com/DownloadImage.aspx?image=/data/books/847/guyatt_ch19-1_fig-19-1-02.jpeg&sec=69033244&BookID=847&ChapterSecID=69031492&imagename= Accessed: October 11, 2017 Copyright © 2017 American Medical Association. All rights reserved