Changing Incidence and Outcomes Following Dialysis-Requiring Acute Kidney Injury Among Critically Ill Adults: A Population-Based Cohort Study Ron Wald,

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Presentation transcript:

Changing Incidence and Outcomes Following Dialysis-Requiring Acute Kidney Injury Among Critically Ill Adults: A Population-Based Cohort Study Ron Wald, MDCM, Eric McArthur, BSc, Neill K.J. Adhikari, MDCM, Sean M. Bagshaw, MD, Karen E.A. Burns, MD, Amit X. Garg, MD, Ziv Harel, MD, Abhijat Kitchlu, MD, C. David Mazer, MD, Danielle M. Nash, MSc, Damon C. Scales, MD, Samuel A. Silver, MD, Joel G. Ray, MD, Jan O. Friedrich, MD American Journal of Kidney Diseases Volume 65, Issue 6, Pages 870-877 (June 2015) DOI: 10.1053/j.ajkd.2014.10.017 Copyright © 2015 National Kidney Foundation, Inc. Terms and Conditions

Figure 1 Development of a cohort comprising adult citizens of Ontario, Canada, who initiated dialysis therapy in an intensive care unit (ICU) in 1996 to 2010. American Journal of Kidney Diseases 2015 65, 870-877DOI: (10.1053/j.ajkd.2014.10.017) Copyright © 2015 National Kidney Foundation, Inc. Terms and Conditions

Figure 2 Annual incidence of dialysis-requiring acute kidney injury (AKI-D) as a proportion of intensive care unit admissions, stratified by hospital teaching status. American Journal of Kidney Diseases 2015 65, 870-877DOI: (10.1053/j.ajkd.2014.10.017) Copyright © 2015 National Kidney Foundation, Inc. Terms and Conditions

Figure 3 The relative utilization of continuous renal replacement therapy (CRRT) and intermittent hemodialysis (IHD) as the first renal replacement therapy modality for the management of dialysis-requiring acute kidney injury among Ontario citizens admitted to an intensive care unit in 1996 to 2010. American Journal of Kidney Diseases 2015 65, 870-877DOI: (10.1053/j.ajkd.2014.10.017) Copyright © 2015 National Kidney Foundation, Inc. Terms and Conditions

Figure 4 The adjusted relationship between era and death by 90 days after an episode of dialysis-requiring acute kidney injury in select patient subgroups. Interaction term P values: cardiac surgery status, 2001-2005: 0.002, 2006-2010: 0.02; sepsis status, 2001-2005: 0.41, 2006-2010: 0.18; chronic kidney disease status, 2001-2005: 0.44, 2006-2010: 0.08. American Journal of Kidney Diseases 2015 65, 870-877DOI: (10.1053/j.ajkd.2014.10.017) Copyright © 2015 National Kidney Foundation, Inc. Terms and Conditions