By:. Asbjørn Kørvel-Hanquist /KU. Anders Koch /SSI. Sjurdur F

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Presentation transcript:

Risk of Otitis Media from modifiable exposures in the Danish national birth cohort By: Asbjørn Kørvel-Hanquist /KU Anders Koch /SSI Sjurdur F. Olsen /SSI Jørgen Lous /SDU Janni Niclasen /KU Jesper Dammeyer /KU Preben Homøe /KU

Disclosure Financial support:

and Social inheritance Prenatal risk attribution Nævne kværner og casselbach studierne med 50% genetisk homogenisitet

18th month/7 years post partum Material and method The Danish National Birth Cohort (DNBC) Data collected from 1996 to 2004 from more than 100,000 pregnancies 2nd trimester 3rd trimester 18th month/7 years post partum

Results Odds-ratio of achieving ≥ 1 episodes of otitis media at the age of 6 months

Results

Results

Results Antibiotics in Pregnancy Increase Children’s Risk of Otitis Media and Ventilation Tubes J Pediatr. 2017 Jan 11. Pedersen TM, Stokholm J, Thorsen J, Mora-Jensen AC, Bisgaard H.

Results

Results

5 Results

Results

Results

Strengths and weaknesses Strengths: -Large size material (N=25,419) -Prospective data collection Weaknesses: -Parent-reported disease outcome -Participation bias -Does not differentiate between different kinds of otitis media

Conclusions We found an association between maternal use of antibiotics during pregnancy and childhood otitis media The association seems stronger for consumption of antibiotics during the 2nd trimester

Thank you for your time