Surgical Versus Medical Therapy for Prosthetic Valve Endocarditis: A Meta-Analysis of 32 Studies Christos G. Mihos, DO, Romain Capoulade, PhD, Evin Yucel,

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Surgical Versus Medical Therapy for Prosthetic Valve Endocarditis: A Meta-Analysis of 32 Studies Christos G. Mihos, DO, Romain Capoulade, PhD, Evin Yucel, MD, Michael H. Picard, MD, Orlando Santana, MD The Annals of Thoracic Surgery Volume 103, Issue 3, Pages 991-1004 (March 2017) DOI: 10.1016/j.athoracsur.2016.09.083 Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Flow diagram depicting the selection of studies for inclusion in the meta-analysis. The Annals of Thoracic Surgery 2017 103, 991-1004DOI: (10.1016/j.athoracsur.2016.09.083) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Forest plot for 30-day mortality. (CI = confidence interval; MH = Mantel-Haenszel.) The Annals of Thoracic Surgery 2017 103, 991-1004DOI: (10.1016/j.athoracsur.2016.09.083) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Forest plot for follow-up survival. (CI = confidence interval; MH = Mantel-Haenszel.) The Annals of Thoracic Surgery 2017 103, 991-1004DOI: (10.1016/j.athoracsur.2016.09.083) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Forest plot for recurrent prosthetic valve endocarditis. (CI = confidence interval; MH = Mantel-Haenszel.) The Annals of Thoracic Surgery 2017 103, 991-1004DOI: (10.1016/j.athoracsur.2016.09.083) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 5 Risk of bias summary graph. The Annals of Thoracic Surgery 2017 103, 991-1004DOI: (10.1016/j.athoracsur.2016.09.083) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions