History of Neurology West Coast Neurology: The 3 Bob’s of UCSF Robert Wartenberg MD Robert Fishman MD Robert B Layzer MD Richard J. Barohn, MD Gertrude and Dewey Ziegler Professor of Neurology The University of Kansas Medical Center
Robert Wartenberg, MD (1887-1956) Born in Garten (German border of Russia) Schooling: Gymnasium in Stuttgart Medical studies: Univ of Kiel, Munich, Freiburg, and Rostock (grad 1919) Mentors: Hocke (Freiburg), Cassier (Berlin), Nonne (Hamburg), Foerster (Breslau) 1925: Fellow Rockefeller Foundation- England/France/USA (Boston under Cushing) 1928: Privatdozent in Freiburg 1933: Head Neurology Clinic Freiburg 1935: Fled Nazi Germany to USA & UCSF rose through academic ranks 1952: UCSF, Clinical Professor of Neurology 1954: UCSF, Professor Emeritus
Robert Wartenberg, MD (1887-1956) Link to golden age of descriptive neurology in Europe Wartenberg’s Eponymy’s Disseminated sensory neuropathy of Wartenberg Wartenberg syndrome or cheiralgia paraesthetica radial sensory neuropathy Sign of Wartenberg – abduction of 5th finger in ulnar nerve palsy Phenomenon of Wartenberg – deviation of jaw of opposite side when touch cornea-also cornea mandibular reflex Roulette Wartenberg - sensory testing device
Robert Wartenberg, MD (1887-1956) Books: Examinations of Reflexes and Diagnostic Test of Neurology (1945) Diagnostic Tests of Neurology (1953) Neuritis, Sensory Neuritis, Neuralgia (1958)
Wartenberg’s Sign Associated Movement of the Thumb Patients palm up on examiners hand Flex fingers against examiners fingers Normally – no thumb movement Pyramidal lesion – thumb abduct, flex, cross palm in opposition Variant - hook top of patient’s index finger against examiners
Wartenberg Wheel A Wartenberg Wheel, also called a Wartenberg Pinwheel or Wartenberg Neurowheel, is a medical device for neurological use. Robert Wartenberg designed the wheel to test nerve reactions (sensitivity) as it rolled systematically across the skin.
Robert Fishman, MD (1924-2012) Born in NYC College: Columbia, age 16 Medical school: University of Pennsylvania Accelerated US Army program in WWII Graduated in 1947, age 22 Internship: Yale then MGH Residency: Columbia, Neurology Co-residents: D. Ziegler & L. Rowland Mentor/chair: H Houston Merritt Korean War - Walter Reed Hospital Chief Resident & Faculty, Columbia Studied blood-brain barrier & CSF physiology and biochemistry 1966: UCSF-Chair Neuro until 1992 President of AAN, AUPN, ANA, ABPN 1993-1997: Editor of Annals of Neurology
Lewis “Bud” Rowland, Dewey Ziegler & Robert Fishman, 2003 . Robert Fishman & Dewey Ziegler
Robert Fishman, MD (1924-2012) Books: Cerebrospinal Fluid in Diseases of the Nervous System (1980 1ST ed., 2nd ed. 1992) Was continuation of H. Houston Merritt’s book - Cerebrospinal Fluid (1938) Fishman, R. 1992 Merritt, HH. 1938
Robert B. Layzer, MD (1931-P) Faculty: Columbia Born in Cleveland, OH College: Harvard Studied French, History, Literature, and acted in Harvard Theater Group Won the Garrison Poetry Prize Medical School: Harvard Residency: Columbia, Neurology Fellowship: Columbia, Neuromuscular Disease Fellow under Lewis Rowland Faculty: Columbia 1967: moved to UCSF Neurology dept. after Dr. Fishman Neuromuscular faculty there his whole career Publications on Periodic Paralysis, Muscle Energy Metabolism, & Motor Unit Hyperactivity State Book: Neuromuscular Manifestation of System Disease (1985 – last edition) Robert B. Layzer, MD (1931-P)