Chee-Seng Tan, MRCP, David Gilligan, FRCPE, Dr Simon Pacey, FRCP 

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Treatment approaches for EGFR-inhibitor-resistant patients with non-small-cell lung cancer  Chee-Seng Tan, MRCP, David Gilligan, FRCPE, Dr Simon Pacey, FRCP  The Lancet Oncology  Volume 16, Issue 9, Pages e447-e459 (September 2015) DOI: 10.1016/S1470-2045(15)00246-6 Copyright © 2015 Elsevier Ltd Terms and Conditions

Figure Timeline in understanding the biology and therapeutic targeting of EGFR-mutant lung cancer EMT=epithelial to mesenchymal transition. SCLC=small-cell lung cancer. MET=mesenchymal to epithelial transition. CTC=circulating tumour cell. ctDNA=circulating tumour DNA. The Lancet Oncology 2015 16, e447-e459DOI: (10.1016/S1470-2045(15)00246-6) Copyright © 2015 Elsevier Ltd Terms and Conditions