Estimation of Phosphate

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Presentation transcript:

Estimation of Phosphate Presented By Assist.Lecturer Aseel Ghassan Daoud M.Sc. In pharmacy/ Clinical laboratory sciences

What are functions of phosphates? What is phosphorus? It is a mineral that combines with other substances to form organic and inorganic phosphate compounds. What are functions of phosphates? Energy production Muscle and nerve function Bone growth Buffer that maintains acid-base balance

What are phosphorus rich foods?

How can the body regulate blood phosphate level be? How much it absorbs from the intestines How much it excretes via kidneys It is also affected by parathyroid hormone (PTH), calcium and vitamin D.

What are symptoms of low phosphate levels?

Causes of hypophosphatemia: Hypercalcaemia and high level of PTH Overuse of diuretics Malnutrition Diabetic ketoacidosis Hypothyroidism Hypokalemia Rickets due to vit. D deficiency Sever burns Alcoholism Chronic antacid use

Causes of hyperphosphatemia: Kidney failure Hypoparathyroidism Hypocalcaemia Diabetic ketoacidosis (first seen) Phosphate supplementation

High phosphorus level can lead to organ damage, why? due to calcification, deposits of calcium phosphate in tissues.

Why are phosphate levels in children higher than in adults? Reference level: 12-60 years : 2.7-4.5 mg/dl Why are phosphate levels in children higher than in adults?