Volume 14, Issue 10, Pages (October 2017)

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Presentation transcript:

Volume 14, Issue 10, Pages 1449-1455 (October 2017) Novel measure of autonomic remodeling associated with sudden cardiac arrest in diabetes Yang Yang, MD, Aapo L. Aro, MD, PhD, Sandeep G. Nair, MD, Reshmy Jayaraman, MD, Kyndaron Reinier, PhD, Carmen Rusinaru, MD, PhD, Audrey Uy-Evanado, MD, Hirad Yarmohammadi, MD, MPH, Jonathan Jui, MD, MPH, Sumeet S. Chugh, MD, FHRS Heart Rhythm Volume 14, Issue 10, Pages 1449-1455 (October 2017) DOI: 10.1016/j.hrthm.2017.07.011 Copyright © 2017 Heart Rhythm Society Terms and Conditions

Figure 1 Diabetic cases lack HRV-HR. HRV-HR is the consistent inverse relationship between HR and HRV in normal physiology, which manifests as a negative linear regression slope in analysis of covariance. Diabetic controls, nondiabetic controls, and nondiabetic cases all have negative regression slopes. However, diabetic cases have a regression slope not significantly different from zero (P = .26) and the slope is significantly different from that of the other subgroups (P = .02). HR = heart rate; HRV = heart rate variability; SDNN = standard deviation of all R-R intervals. Heart Rhythm 2017 14, 1449-1455DOI: (10.1016/j.hrthm.2017.07.011) Copyright © 2017 Heart Rhythm Society Terms and Conditions

Figure 2 HRV-HR in the different groups of patients. Beat-to-beat variability comparison between (A) diabetic cases and (B) diabetic controls, nondiabetic controls, and nondiabetic cases. Note the presence of HRV-HR in all other subgroups as visualized by increasing variability at lower HR. This is not seen in diabetic cases. HR = heart rate; HRV = heart rate variability. Heart Rhythm 2017 14, 1449-1455DOI: (10.1016/j.hrthm.2017.07.011) Copyright © 2017 Heart Rhythm Society Terms and Conditions