IN THE NAME OF INNOVATION The Bracco Group 90 YEARS IN THE NAME OF INNOVATION

1927-2017 The milestones

Commitment to Research and Innovation Investment of 9% of reference turnover in R&D for diagnostic imaging and advanced medical devices, with a portfolio comprising over 1,800 patents and 7 R&D centres in the world 7 R&D CENTRES ITALY Colleretto Giacosa - Ivrea SWITZERLAND Geneva Lausanne USA Freemont - Silicon Valley Princeton (New Jersey) Minneapolis (Minnesota) Maple Grove (Minnesota)

Diagnostic Imaging Modalities Products and solutions portfolio for all diagnostic imaging modalities: X-ray Imaging (including Computed Tomography-CT, Interventional Radiology, and Cardiac Catheterization), Magnetic Resonance Imaging (MRI), Contrast Enhanced Ultrasound (CEUS) and Nuclear Medicine X-Ray CT Magnetic Resonance Ultrasound Nuclear Medicine

Cost of drug R&D The average amount spent to bring a new prescription drug to market more than doubled in about 10 years

A paradigm shift: collaboration Open innovation programs have become a near-universal model for R&D Companies offer university researchers access to funds and resources Academic scientists bring in-depth expertise and basic research data

Collaboration between Bracco and Universities Exchange of ideas and expertises, focusing on mutual needs

Where open innovation leads to To create value for the company and the communities

Our Open Innovation instruments Exploiting Open R&D for Drug discovery, Non-clinical development and Process optimisation Research contracts Exchange of people Spin-offs Scientific networks Data refer to the Italian Bracco R&D

Research contracts Funding of base and applied research programs to enable the Company to find / characterise / optimise products and processes Sum of Research Contracts with Universities: last 10 years

Moving people: from University to Bracco Students have the chance to make experience in industrial laboratories, before or immediately after their graduation Presence of students at Bracco Research Centre: last 10 years

Moving people: from Bracco to University Professionals can share their expertise and product-oriented knowledge by teaching in Universities Courses/workshops led by Bracco researchers: last 10 years

Spin-off creation application of imaging technologies in preclinical drug R&D Using both Bracco and University of Turin facilities and instruments

Scientific networking > 20 meetings organised in 10 years Students and external experts are invited Relationship building Scientific Park

Thank you!