Cost effectiveness of cancer treatment in Taiwan

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Presentation transcript:

Cost effectiveness of cancer treatment in Taiwan Mei-Chuan Hung, Wu-Wei Lai, Helen H.W. Chen, Jenq-Chang Lee, Yih-Jyh Lin, Jenn-Ren Hsiao, Ya-Min Cheng, Yan-Shen Shan, Wu- Chou Su, Jung-Der Wang Journal of the Formosan Medical Association Volume 115, Issue 8, Pages 609-618 (August 2016) DOI: 10.1016/j.jfma.2016.04.002 Copyright © 2016 Terms and Conditions

Figure 1 Flow diagram of the computation process for cost per QALY. We linked the Taiwan Cancer Registry and NHIRD to the Taiwan Mortality Registry and extrapolated the results to obtain the lifetime survival functions for patient cohorts with different illnesses, which were either adjusted with the QoL data measured in EQ-5D to obtain the QALE, or multiplied by the average monthly cost to obtain the lifetime cost after being adjusted for an annual discount rate of 3%. The cost per QALY was then calculated by dividing the lifetime cost by QALE (with 3% discount). EQ-5D=EuroQoL five-dimension; NHIRD=National Health Insurance Research Database; QALE=quality-adjusted life expectancy; QALY=quality-adjusted life year; QoL=quality of life. Journal of the Formosan Medical Association 2016 115, 609-618DOI: (10.1016/j.jfma.2016.04.002) Copyright © 2016 Terms and Conditions

Figure 2 Comparison of cost per QALY (3% discount) for different types of cancers, patients under PMV, and patients with ESRD, stratified by gender: (A) males and (B) females. ESRD=end-stage renal disease; PMV=prolonged mechanical ventilation; QALE=quality-adjusted life expectancy; QALY=quality-adjusted life year. Journal of the Formosan Medical Association 2016 115, 609-618DOI: (10.1016/j.jfma.2016.04.002) Copyright © 2016 Terms and Conditions

Figure A1 QALE for males with colorectal cancer. A total of 43,731 patients were followed for 13 years, and their data were extrapolated throughout lifetime to obtain the survival function, which was adjusted by the utility values measured with the EQ-5D (N=817). The total area under the quality-adjusted survival curve (shaded areas) was then summed up as the QALE, which was 9.9±0.1 QALYs. EQ-5D=EuroQoL five-dimension; QALE=quality-adjusted life expectancy; QALY=quality-adjusted life year. Journal of the Formosan Medical Association 2016 115, 609-618DOI: (10.1016/j.jfma.2016.04.002) Copyright © 2016 Terms and Conditions

Figure A2 Lifetime healthcare expenditures for males with colorectal cancer. The monthly survival probability (N=43,731) was multiplied by the monthly expenses and summed up for a lifetime (shaded areas), which amounts to US$24,677±1741 (3% discount). Journal of the Formosan Medical Association 2016 115, 609-618DOI: (10.1016/j.jfma.2016.04.002) Copyright © 2016 Terms and Conditions