Body mass index affects knee joint mechanics during gait differently with and without moderate knee osteoarthritis  Graeme T. Harding, Cheryl L. Hubley-Kozey,

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Body mass index affects knee joint mechanics during gait differently with and without moderate knee osteoarthritis  Graeme T. Harding, Cheryl L. Hubley-Kozey, Michael J. Dunbar, William D. Stanish, Janie L. Astephen Wilson  Osteoarthritis and Cartilage  Volume 20, Issue 11, Pages 1234-1242 (November 2012) DOI: 10.1016/j.joca.2012.08.004 Copyright © 2012 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 Knee adduction moment PC3. (a) The knee adduction moment mean waveforms for the asymptomatic and moderate OA groups are shown. (b) Mean knee adduction moment waveforms for each of the three BMI categories is shown. (c) PC3 of the knee adduction moment represented the range in the waveform during stance phase, high PC3 scores indicated high first peak adduction moments relative to mid-late stance values. (d) Representative high (healthy weight direction) and low (overweight/obese direction) subject waveforms (95th and 5th percentiles) demonstrate the interpretation of PC3. Osteoarthritis and Cartilage 2012 20, 1234-1242DOI: (10.1016/j.joca.2012.08.004) Copyright © 2012 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 Knee rotation moment PC3. (a) The knee internal rotation moment mean waveforms for the asymptomatic and moderate OA groups are shown. (b) Mean knee internal rotation moment waveforms for each of the three BMI categories is shown. (c) PC3 of the knee internal rotation moment represented the range in the waveform during stance phase. (d) Representative high (overweight/healthy weight direction) and low (obese direction) subject waveforms (95th and 5th percentiles) demonstrate the interpretation of PC3. Osteoarthritis and Cartilage 2012 20, 1234-1242DOI: (10.1016/j.joca.2012.08.004) Copyright © 2012 Osteoarthritis Research Society International Terms and Conditions

Fig. 3 Knee flexion angle interaction effect. (a) PC3 of the knee flexion angle represented the range during the stance phase. (b) Mean knee flexion angle waveforms for each of the six subject groups based on BMI category and moderate OA disease presence. (c) Representative high and low subject waveforms (95th and 5th percentiles) demonstrate the interpretation of PC3. (d) Interaction between obesity and moderate knee OA in PC3 of the knee flexion angle. Osteoarthritis and Cartilage 2012 20, 1234-1242DOI: (10.1016/j.joca.2012.08.004) Copyright © 2012 Osteoarthritis Research Society International Terms and Conditions

Fig. 4 Knee flexion moment interaction effect. (a) PC2 of the knee flexion moment represented the range during the stance phase. (b) Mean knee flexion moment waveforms for each of the six subject groups based on BMI category and moderate OA disease presence. (c) Representative high and low subject waveforms (95th and 5th percentiles) demonstrate the interpretation of PC2. (d) Interaction between obesity and moderate knee OA in PC2 of the knee flexion moment. Osteoarthritis and Cartilage 2012 20, 1234-1242DOI: (10.1016/j.joca.2012.08.004) Copyright © 2012 Osteoarthritis Research Society International Terms and Conditions