Cancer Prevention and Screening Stephen Duffy Module lead Ivana Sestak Deputy

Module contents Methods of epidemiological research How to ascertain the causes of disease? Common causes of cancer Prevention strategies Evaluation and implementation Screening for cancer

Epidemiological methods Discovery of the correlates and cancer Who gets it and who doesn’t? Age, sex, geography How to establish causal action? Affluent women have higher rates of breast cancer than deprived women, but WHY?

Cancer Prevention Can we change lifestyles to prevent cancer? Smoking Obesity Alcohol Chemoprevention Hormones to prevent breast cancer Vaccines against pathogens causing cancer

Question Smoking is estimated to cause 20% of cancers Does this mean that if a smoker gives up smoking the best to be hoped for is a 20% reduction in cancer risk?

Cancer Screening Complexities of evaluation Lead time, delayed benefit Screening in practice in the UK Breast Cervix Colorectum Potential other cancer screening activities Prostate, lung, ovary

Course structure Unit Value: 0.5 Total Student Study Hours: 75 Taught Hours: 15 Private Study Hours: 50-60 Courses: MSc Cancer Therapeutics MSc Molecular Pathology & Genomics Semester: Two Timetable: Tuesday 12:30 – 14:00 Summary of Assessment Method: Exam (60%) In Course Assessment – 40%

Course structure Lectures – about 5 sessions Small tutorial groups of between 6-8 students – about three sessions

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