Platelet-Rich Plasma as an Adjunctive Therapy for the Management of a Severe Chronic Distal Limb Wound in a Foal Catalina López, MVZ, PhD, Jorge U. Carmona,

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Platelet-Rich Plasma as an Adjunctive Therapy for the Management of a Severe Chronic Distal Limb Wound in a Foal Catalina López, MVZ, PhD, Jorge U. Carmona, MVZ, MSc, PhD Journal of Equine Veterinary Science Volume 34, Issue 9, Pages 1128-1133 (September 2014) DOI: 10.1016/j.jevs.2014.06.007 Copyright © 2014 Elsevier Inc. Terms and Conditions

Fig. 1 (A) The wound was severely contaminated and presented a bad smell. (B) Swollen zone with exaggerated granulation tissue and an osseous sequestrum exposition. (C) Lateral radiograph image demonstrating proliferative exostosis and fragments of demineralized bone. Journal of Equine Veterinary Science 2014 34, 1128-1133DOI: (10.1016/j.jevs.2014.06.007) Copyright © 2014 Elsevier Inc. Terms and Conditions

Fig. 2 (A) The granulation tissue was debulked, and the bone exostosis was removed. (B) Activated platelet-rich plasma was injected at the end of surgery. (C) Dark detritus around the wound and the exposed bone. Journal of Equine Veterinary Science 2014 34, 1128-1133DOI: (10.1016/j.jevs.2014.06.007) Copyright © 2014 Elsevier Inc. Terms and Conditions

Fig. 3 (A) Important wound contraction and epithelialization with exuberant granulation tissue at the eighth postoperative day. Platelet-rich plasma is injected on and around the wound borders. (B) After 2 weeks, the wound had diminished by 50% with respect to the initial lesion. (C) After 4 weeks, the size of the wound had diminished by another 40% with respect to the initial lesion. Journal of Equine Veterinary Science 2014 34, 1128-1133DOI: (10.1016/j.jevs.2014.06.007) Copyright © 2014 Elsevier Inc. Terms and Conditions

Fig. 4 (A) At 6 weeks, the wound was almost completely healed. (B) Lateral radiograph showing cortical bone remodeling without superficial bone proliferation in the cannon bone. (C) Complete wound healing with a very small scar 1 month after surgery. Journal of Equine Veterinary Science 2014 34, 1128-1133DOI: (10.1016/j.jevs.2014.06.007) Copyright © 2014 Elsevier Inc. Terms and Conditions