Liceo scientifico Francesco Redi Liver cancer Riccardo Castiglia Prof.ssa Vannuccini
Liver structure Principal components PORTAL VEIN HEPATIC LOBUL HEPATIC ARTERY
Liver functions Production of bile Production of enzymes Metabolis functios(glucogenesis,gliconelosis,glicogenosintesis) Protein metabolism Synthesis of cholesterol and tryglyceridis Detoxification
Liver cancer (epatocarcinoma) Secondary Primary (primitivo) MALICIOUS This comes from metastases HEPATOCARCINOMA COLANGIOCARCINOMA BENIGN HEMANGIOMA SIMPLE ADENOMA
SPREAD WORLDWIDE The liver cancer rapresents the third principal cause of tumor death, after lugs and stomach cancer WEST 5 people on 100’000 meet liver cancer AFRICA 110 people on 100’000 meet liver cancer, especially in Mozambigo EAST 30 people on 100’000 meet liver cancer
Causes 60% hepatitis cirrhosis 25% viral hepatitis 10% hemacromatosis 5% Sex ; age; heredity; alcool; smoke; drugs
Symptoms HEPATOMEGALY ADDOMINAL PAIN JAUNDICE SPLEEN ENLARGED CIRROSIS (liver enlarged) ADDOMINAL PAIN (it often results in peritonitis) JAUNDICE (yellowing coloration of the skin) SPLEEN ENLARGED CIRROSIS (it often causes weight loss and fever) ASCITES
Treatemet Surgery ( successefull of 25%) Liver transplantation(successefull of 24%) Chemioterapy (successefull of 35%) Interior residential treatments (successefull of 15 %) Chemioembolization (successefull of 14%) SURVIVAL Percentage taken from AIOM (italian associatio of medical oncology) In Italy: the 17% of men and 16% of women, that have met that neoplasms, are still in life after 5 years from the diagnosis
GRAZIE PER L’ATTENZIONE!!!!!