Clinical outcomes among patients with chronic low back pain treated with pregabaline monotherapy in fort portal regional referral hospital, “case series”

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Presentation transcript:

clinical outcomes among patients with chronic low back pain treated with pregabaline monotherapy in fort portal regional referral hospital, “case series” BY : Pariyo bonane Godfrey ORTHOPAEDIC SURGEON, FORT PORTAL REGIONAL REFERRAL HOSPITAL, uganda

BACKGROUND Chronic low back pain associated with radiculopathy is a common reason for physicians visit but no guidelines are available for management of these patients in Uganda. Studies in Germany using pregabaline monotherapy have either shown no or inferior effect to combination therapy in USA on resolution of symptoms (Baron Retal 2010, Luca Cetal 2009). We evaluated clinical response to pregabaline monotherapy on low back pain associated with radiculopathy at the orthopaedic outpatient clinic of Fort portal regional referral hospital in Western Uganda.

METHODS In this prospective study conducted from February to July 2015, 15 patients with chronic low back pain associated with radiculopathy exceeding 3 months were seen in the orthopaedic outpatient clinic at Fort portal regional referral hospital . All were treated with a 4 week course of oral pregabaline (75mg taken once a day )and evaluated for clinical improvement. Visual Analogue score (VAS) for pain was used to assess the degree of pain among patients after 4 weeks of treatment. Structured questionnaires were used to capture sociodemographic and clinical data.

VISUAL ANALOQUE SCORE FOR PAIN ASSESMENT

RESULTS Of the 15 patients 10 were females and 5 were males, with age range of 28-75 years and mean age 53 years Before treatment with pregabaline all the patients had visual analogue score 8-10 After 4 weeks of treatment with oral pregabaline 13 patients showed significant improvement with reduction in visual analogue score of 0-2 while 2 patients had modest reduction in visual analogue score of 6-8

Gender Total Male(5) Female(10) (15) Age range 28-75 Mean(58) VAS Number of patients VAS Before treatment 8-10 15 VAS After treatment 0-2 13 6-8 02

CONCLUSION Oral pregabaline has good clinical effect on the treatment of patients with low back pain associated with radiculopathy. However further research is needed with sufficient sample , randomisation and longer follow up.

MANY THANKS & WELCOME TO FORTPORTAL , UGANDA