XPC Control Target A/D Converter P10021 LVAD Motor Controller 4051 MUX Counter Internal Clock In/Out LVAD Ground 15V Out/In 4051 DEMUX Counter Motor Controller 2 Sum. Op-Amplifiers 4 Diff. Op-Amplifiers 4051 DEMUX Counter Internal Clock PWM Generator (4 Amplifiers) Out/In Ground 15V In/Out Counter 4051 MUX Voltage Regulator 5, 12, 15, Ground 13 Pins of DV 15

Concept Selection: Signal Transmission System B C D MICS 400 - 405 MHz Bluetooth 2.4 GHz OFDM Over One Wire 2 Multiplexed Wires Selection Criteria Weight Rating Notes Wtd Inter-group compatibility 2   4 4.00 3 6.00 Interference 5 Reserved Medical Band 15 1 Unlicensed 2.4GHz Band Orthogonal Signals 15.00 Size 3x5x10 mm 8 6x6x1 mm 6 Requires multiple parts 2.00 Data Rate 800kbps 3 Mbps 9 500kbps plus wire transfer 12.00 Wire Transfer 9.00 Power -16dBm 12 -6 to 4 dBm Wire number reduction 2 wires 20 3 wires 4 wires 5.00 Availability of Parts 24-lead? Widely 10.00 20.00 Scope of Project falls within rigorous time line Difficult test platform Unfamiliar topic 24.00 Reliability Possible loss of signal 16 Attenuation of frequency Partially wired for control 32.00 Wired connection Security Wireless Hacking Blue Jacking Wired Signal Low probability of error 7 Signals sent in separate packets Signals sent on orthogonal channels 21.00 Less signal processing 28.00 Total Score 104.00 93.00 132.00 146.00

Wireless Signal Transmission (INT) Interior Electronics (Proposed) Pump Transmitter 12-bit A/D 6 Total 72 bits 72 bits 6 signals HESA Hall Effect Sensor Array 2 Total Differential/Summing Amps 6 Total 5V 8 signals 3 currents Receiver Motor Controller PWM Amps 4 Total Motor 12V 5 bits 4 currents AMB Active Magnetic Bearing 2 Total 15V Clock FPGA For Signal Processing

Miniaturization Project Wireless Signal Transmission (EXT) Miniaturization Project Exterior Electronics (Proposed) Control XPc Target 6 signals FPGA For Signal Processing Receiver 72 bits 72 bits Motor Control Signal PWM Control Signals (4 or 8) 5 bits Transmitter 5 bits Clock Benefits Eliminates all signal wires Cons 300kHz channels require data in packets Higher bit error rate Requires 2 Wires 15 V Line Ground Line

Multi-Channel Single Wire Signal (INT) Interior Electronics (Proposed) Pump OFDM Encoder 12-bit A/D 6 Total 72 bits 6 signals HESA Hall Effect Sensor Array 2 Total Transmitter Differential/Summing Amps 6 Total 5V 8 signals s(t) Receiver Motor 12V 3 currents OFDM Decoder Motor Controller AMB Active Magnetic Bearing 2 Total 15V 4 currents PWM Amps 4 Total

Miniaturization Project Multi-Channel Single Wire Signal (EXT) Miniaturization Project Exterior Electronics (Proposed) Control XPc Target 6 signals OFDM Encoder/Decoder Receiver 72 bits Motor Control Signal s(t) PWM Control Signals (4 or 8) 5 bits Transmitter Clock Requires 3 Wires 15 V Line Ground Line 1 Signal Wire Benefits Allows for wider bandwidth Decrease probability of error More control of channel

Concept Selection - Materials   Titanium Silicone UHMWPE Polyurethane Selection Criteria Weight Rating Notes Wtd Ease of Fabrication 7 5 Machine Block 35 8 Room Temp. Cast or Overcoating 56 Unknown FDA Approved for Similar Applications 10 Abiocor control case 80 2 Many 16 Prosthetics 40 Abiocor pump Availability Off-the-shelf Special order 25 9 45 3 Angioflex, trademarked 15 High Thermal Conductance 15 W/m-K 21 0.3 W/m-K 0.5 W/m-K Assumed < 1W/m-K Low Wireless Interference 18 Low Weight 6 4.4 g/cc 1 g/cc 54 0.9 g/cc 1.2 g/cc High Durability No corrosion 100 Inert 70 Total Score 289 278 263 249 Rank 1 4

Wire- “Less” Proposal (INT) Interior Electronics (Proposed) Pump 6:1 Multiplexer Differential/Summing Amps 6 Total HESA Hall Effect Sensor Array 2 Total 5V 8 signals Wired Signal Motor Controller Motor 3 currents 12V 1:5 Multiplexer Wired Signal PWM Amps 4 Total 8 currents AMB Active Magnetic Bearing 2 Total 15V Clock 3-bit Counter

Miniaturization Project Wire- “Less” Proposal (EXT) Miniaturization Project Exterior Electronics (Proposed) 6 position signals Wired Signal Control XPc Target 1:6 Multiplexer 1 Relay Signal 3-bit Counter Clock Counter Wired Signal 5:1 Multiplexer 4 PWM Control Signals Benefits Cost Effective Wired signal more reliable than wireless Cons Signal only available fraction of time Will require synchronization commands with project 10021 Requires 4 Wires 15 V Line Ground Line 2 Signal Wire (1 Clock sync wire)