Andrew M Wilson, MD, Paul M O'Byrne, MB, Krishnan Parameswaran, MD

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Leukotriene receptor antagonists for allergic rhinitis: a systematic review and meta- analysis Andrew M Wilson, MD, Paul M O'Byrne, MB, Krishnan Parameswaran, MD The American Journal of Medicine Volume 116, Issue 5, Pages 338-344 (March 2004) DOI: 10.1016/j.amjmed.2003.10.030

Figure 1 Flow chart illustrating the results of the research strategy. The American Journal of Medicine 2004 116, 338-344DOI: (10.1016/j.amjmed.2003.10.030)

Figure 2 Comparison of leukotriene receptor antagonists and placebo. The plot of weighted mean difference with 95% confidence intervals for composite rhinitis symptom scores is expressed as a percentage of the maximum score. There was significant variation in results among studies (P = 0.01 for heterogeneity). The American Journal of Medicine 2004 116, 338-344DOI: (10.1016/j.amjmed.2003.10.030)

Figure 3 Comparison of leukotriene receptor antagonists and nasal corticosteroids. The plot of weighted mean difference with 95% confidence intervals for composite rhinitis symptom scores is expressed as a percentage of the maximum score. There was significant variation in results among studies (P = 0.0002 for heterogeneity). The American Journal of Medicine 2004 116, 338-344DOI: (10.1016/j.amjmed.2003.10.030)

Figure 4 Comparison of leukotriene receptor antagonists and antihistamines. The plot of weighted mean difference with 95% confidence intervals for composite rhinitis symptom scores is expressed as a percentage of the maximum score. The results did not vary among the studies (P = 0.13 for heterogeneity). There was no significant difference between leukotriene receptor antagonists and antihistamines. The American Journal of Medicine 2004 116, 338-344DOI: (10.1016/j.amjmed.2003.10.030)