Journal of Food and Drug Analysis

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Journal of Food and Drug Analysis Exploration of Wedelia chinensis leaf-assisted silver nanoparticles for antioxidant, antibacterial and in vitro cytotoxic applications Merina Paul Das, Jeyanthi Rebecca Livingstone, Pandiyarasan Veluswamy, Jayabrata Das Journal of Food and Drug Analysis DOI: 10.1016/j.jfda.2017.07.014 Copyright © 2017 Terms and Conditions

Fig. 1 (a) Color changes after addition of different concentration of plant extract (1–10% v/v), (b) corresponding SPR spectra of AgNPs, and (c) time dependent absorption spectra of AgNPs. Journal of Food and Drug Analysis DOI: (10.1016/j.jfda.2017.07.014) Copyright © 2017 Terms and Conditions

Fig. 2 Plausible mechanism of biosynthesis of AgNPs. Journal of Food and Drug Analysis DOI: (10.1016/j.jfda.2017.07.014) Copyright © 2017 Terms and Conditions

Fig. 3 (a and b) TEM micrographs of biosynthesized spherical shaped AgNPs. Journal of Food and Drug Analysis DOI: (10.1016/j.jfda.2017.07.014) Copyright © 2017 Terms and Conditions

Fig. 4 (a) EDX, (b) XRD, and (c) XPS spectra of AgNPs synthesized using WLE. Journal of Food and Drug Analysis DOI: (10.1016/j.jfda.2017.07.014) Copyright © 2017 Terms and Conditions

Fig. 5 FTIR spectrum of (a) WLE (alone) and (b) synthesized AgNPs from WLE. Journal of Food and Drug Analysis DOI: (10.1016/j.jfda.2017.07.014) Copyright © 2017 Terms and Conditions

Fig. 6 (a) DPPH free radical scavenging activity, and (b) Reducing power of WLE, biosynthesized AgNPs, and AA (L-ascorbic acid) at different concentrations (12.5–200 μg/mL). Journal of Food and Drug Analysis DOI: (10.1016/j.jfda.2017.07.014) Copyright © 2017 Terms and Conditions

Fig. 7 Antibacterial activity (a) on Gram-negative bacteria (E. coli), (b) on Gram-positive bacteria (L. monocytogenes), and (c) mean zone of inhibition (mm) of biogenic AgNPs synthesized against pathogenic bacterial strains. Journal of Food and Drug Analysis DOI: (10.1016/j.jfda.2017.07.014) Copyright © 2017 Terms and Conditions

Fig. 8 Inverted microscopic images of Hep G2 cell lines (10× magnification) after 24 h incubation (a) control cell lines, (b) AgNPs treated cell lines at IC50, (c) AgNPs (200 μg/mL) treated cell lines, (d) effects of AgNPs on the viability of Hep G2 cell lines, and (e) effect of AgNPs on LDH activity on Hep G2 cell lines. (*) indicates a statistically significant difference compared to control (p < 0.05). Journal of Food and Drug Analysis DOI: (10.1016/j.jfda.2017.07.014) Copyright © 2017 Terms and Conditions

Journal of Food and Drug Analysis DOI: (10.1016/j.jfda.2017.07.014) Copyright © 2017 Terms and Conditions